METHYLAL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C3H8O2
Molecular Weight	76.0944
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COCOC

InChI

InChIKey=NKDDWNXOKDWJAK-UHFFFAOYSA-N

InChI=1S/C3H8O2/c1-4-3-5-2/h3H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C3H8O2
Molecular Weight	76.0944
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/24148961 | https://www.ncbi.nlm.nih.gov/pubmed/24000449

Methylal, also known, as dimethoxymethane is widely used as a solvent and in the manufacture of perfumes, resins, adhesives. Besides methylal is applied to increase the octane number of gasoline. This compound can be toxic if the average exposure concentration in workplace air will be above 3100 mg/m(3).

Approval Year

PubMed

Title	Date	PubMed
Conformations of dimethoxymethane: matrix isolation infrared and ab initio studies.	2002 Feb	11905532
Relative reactivities of carbonyl and thiocarbonyl groups toward dimethoxycarbene: two new dimethoxythiiranes.	2002 May 3	11981903
Tandem 1,4-addition reactions with benzene and alkylated benzenes promoted by pentaammineosmium(II).	2002 Nov 6	12405835
Strategies for heterocyclic construction via novel multicomponent reactions based on isocyanides and nucleophilic carbenes.	2003 Dec	14674781
Matrix isolation infrared and ab initio study of the conformations of 2,2-dimethoxypropane.	2003 May	12714073
Diastereo- and enantioselective dearomatization of rhenium-bound naphthalenes.	2004 Apr 2	15049617
The external-anomeric torsional effect.	2005 Apr 11	15780251
Selective oxidation of methanol and ethanol on supported ruthenium oxide clusters at low temperatures.	2005 Feb 17	16851207
Ultraviolet photolysis of CH2I2 in methanol: O-H insertion and HI elimination reactions to form a dimethoxymethane product.	2005 Feb 17	16833436
New thermal source of dimethoxycarbene leading to zwitterionic intermediates and 2:1 stoichiometry in reaction with electrophilic alkenes.	2005 Feb 3	15673271
Active control of methanol carbonylation selectivity over Au/carbon anode by electrochemical potential.	2005 May 12	16852087
New entry into beta-lactams via reaction of dimethoxycarbene with isocyanates.	2006 Jul 6	16805567
The local environment of Cu+ in Cu-Y zeolite and its relationship to the synthesis of dimethyl carbonate.	2006 Jun 22	16800460
Reaction of dimethoxycarbene-DMAD zwitterion with 1,2-diones and anhydrides: a novel synthesis of highly substituted dihydrofurans and spirodihydrofurans.	2006 Mar 17	16526779
Synthesis of novel sigma-receptor ligands from methyl alpha-D-mannopyranoside.	2006 Oct 16	16854396
Noncovalent interactions and internal dynamics in dimethoxymethane-water.	2007	17455188
Evidence for a concerted [4 + 1]- cycloaddition between electron-rich carbenes and electron-deficient dienes.	2007 Dec 20	18027955
Atoms in molecules interpretation of the anomeric effect in the O--C--O unit.	2007 Jul 15	17330885
Imaging momentum orbital densities of conformationally versatile molecules: a benchmark theoretical study of the molecular and electronic structures of dimethoxymethane.	2007 Jul 5	17566995
Reactions of dimethoxycarbene with dimethyl 2,3-dicycanomaleate and fumarate.	2007 Jun 21	17542600
Selective oxidation of methanol to dimethoxymethane under mild conditions over V2O5/TiO2 with enhanced surface acidity.	2007 Jun 7	17520126
Amorphous oxide as a novel efficient catalyst for direct selective oxidation of methanol to dimethoxymethane.	2008 Feb 21	18253530
(S)-1,5-Dibenzyl-3-tert-butyl-imidazol-idin-4-one.	2008 Jun 25	21202954
A novel metered dose transdermal spray formulation for oxybutynin.	2008 Nov	21369433
Vapor-phase carbonylation of dimethoxymethane over H-Faujasite.	2009	19452505
Reactivity of heteropolytungstate and heteropolymolybdate metal transition salts in the synthesis of dimethyl carbonate from methanol and CO₂.	2010 Jul 23	20717536
N-(4-Chloro-pyridin-2-yl)-N-meth-oxy-methyl-4-methyl-benzene-sulfonamide.	2010 Nov 27	21589598
N-(4-Chloro-pyridin-2-yl)-N-(4-methyl-phenyl-sulfon-yl)acetamide.	2010 Nov 27	21589597

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:59:44 GMT 2023` Edited by `admin` on `Fri Dec 15 17:59:44 GMT 2023`
Record UNII	7H1M4G2NUE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

METHYLAL

Official Name

English

FORMAL

Common Name

English

METHYLENE DIMETHYL ETHER

Common Name

English

METHYLAL [MI]

Common Name

English

METHYLAL [INCI]

Common Name

English

METHYLAL [HSDB]

Common Name

English

METHANE, DIMETHOXY-

Systematic Name

English

Methylal [WHO-DD]

Common Name

English

2,4-DIOXAPENTANE

Systematic Name

English

DIMETHOXYMETHANE

Systematic Name

English

FORMALDEHYDE DIMETHYL ACETAL

Systematic Name

English

Code System Code Type Description

WIKIPEDIA

DIMETHOXYMETHANE