U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry MIXED
Molecular Formula C19H40N2.2I
Molecular Weight 550.3432
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MEBEZONIUM IODIDE

SMILES

[I-].[I-].C[N+](C)(C)C1CCC(CC2CCC(CC2)[N+](C)(C)C)CC1

InChI

InChIKey=CWPAAKNARYMZLM-UHFFFAOYSA-L
InChI=1S/C19H40N2.2HI/c1-20(2,3)18-11-7-16(8-12-18)15-17-9-13-19(14-10-17)21(4,5)6;;/h16-19H,7-15H2,1-6H3;2*1H/q+2;;/p-2

HIDE SMILES / InChI

Molecular Formula HI
Molecular Weight 127.9124
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C19H40N2
Molecular Weight 296.5343
Charge 2
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Mebezonium is a component of T-61/Tanax (a combination of embutramide, mebezonium iodide, tetracaine hydrochloride), a product which is indicated for euthanasia in animals. The drug was withdrawn from the market by the manufacturer's decision.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
T-61 EUTHANASIA SOLUTION

Approved Use

Euthanasia in domestic animals.
PubMed

PubMed

TitleDatePubMed
Screening procedure for eight quaternary nitrogen muscle relaxants in blood by high-performance liquid chromatography-electrospray ionization mass spectrometry.
2003 Jun 5
Dimethylformamide metabolism following self-harm using a veterinary euthanasia product.
2010 Aug

Sample Use Guides

In Vivo Use Guide
Dogs: Intravenous injection: 0.3 ml/kg. Intracardiac injection: Up to 10 kg: 7-10 ml/animal. Over 10 kg: 10 ml first, and as soon as the animal is lying, another dose of 3-10 ml, depending on the size of the animal, intrapulmonary or intracardiac. - Cats: Intravenous injection: 0.3 ml/kg. Intracardiac/intrapulmonary injection: Cats of few days of life old: 1 ml/animal. Cats older than six months: 3 ml/animal. Cats older than six months of age: 5 ml/animal. Cats over 5 kg: 10 ml/animal.  - Marten and other fur animals: Injection intracardiac/intrapulmonary 0.5 - 1 ml/animal. - Horses and cattle not intended for animal or human consumption: Recommended dose of 4-6 ml/50 kg, injected intravenously.  - Other animals: Such as ornamental birds and small laboratory animals: 0.2 to 2 ml/animal
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 05:27:14 GMT 2023
Edited
by admin
on Sat Dec 16 05:27:14 GMT 2023
Record UNII
7GVF119EM8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MEBEZONIUM IODIDE
GREEN BOOK   INN  
INN  
Official Name English
MEBENZONIUM IODIDE
Common Name English
CYCLOHEXANAMINIUM, 4,4'-METHYLENEBIS(N,N,N-TRIMETHYL-, IODIDE (1:2)
Systematic Name English
(METHYLENEDI-1,4-CYCLOHEXYLENE)BIS(TRIMETHYLAMMONIUM IODIDE)
Common Name English
mebezonium iodide [INN]
Common Name English
MEBEZONIUM IODIDE [GREEN BOOK]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29696
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
Code System Code Type Description
PUBCHEM
71849
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
PRIMARY
ECHA (EC/EINECS)
231-676-7
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
PRIMARY
EPA CompTox
DTXSID20998132
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
PRIMARY
NCI_THESAURUS
C66058
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
PRIMARY
INN
2154
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
PRIMARY
SMS_ID
100000081750
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110994
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
PRIMARY
EVMPD
SUB08663MIG
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
PRIMARY
CAS
7681-78-9
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
PRIMARY
MESH
C059325
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
PRIMARY
FDA UNII
7GVF119EM8
Created by admin on Sat Dec 16 05:27:14 GMT 2023 , Edited by admin on Sat Dec 16 05:27:14 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY