Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C37H36N2O10S3 |
| Molecular Weight | 764.884 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN(CC1=CC=CC(=C1)S(O)(=O)=O)C2=CC=C(C=C2)C(=C3C=CC(C=C3)=[N+](CC)CC4=CC=CC(=C4)S(O)(=O)=O)C5=C(C=C(O)C=C5)S([O-])(=O)=O
InChI
InChIKey=VVJKKKDJADMKNM-UHFFFAOYSA-N
InChI=1S/C37H36N2O10S3/c1-3-38(24-26-7-5-9-33(21-26)50(41,42)43)30-15-11-28(12-16-30)37(35-20-19-32(40)23-36(35)52(47,48)49)29-13-17-31(18-14-29)39(4-2)25-27-8-6-10-34(22-27)51(44,45)46/h5-23H,3-4,24-25H2,1-2H3,(H3,41,42,43,44,45,46,47,48,49)
| Molecular Formula | C37H36N2O10S3 |
| Molecular Weight | 764.884 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Overexpression of G1/S cyclins and PCNA and their relationship to tyrosine phosphorylation and dephosphorylation during tumor promotion by metanil yellow and malachite green. | 2000 Jul 27 |
|
| Malachite green induced malignant transformation of Syrian hamster embryo (SHE) cells in primary culture: transformation is associated with enhanced expression of altered p53, bcl-2 and decreased sensitivity to apoptosis. | 2000 Mar |
|
| Effect of metanil yellow and malachite green on DNA synthesis in N-nitrosodiethylamine induced preneoplastic rat livers. | 2001 Sep |
|
| Tumor promotion by metanil yellow and malachite green during rat hepatocarcinogenesis is associated with dysregulated expression of cell cycle regulatory proteins. | 2003 |
|
| Hyperphosphorylation of extracellular regulated kinase 2 (ERK2) and inhibition of JNK2 phosphorylation are associated with increased S-phase during transformation of Syrian hamster embryo cells by Malachite Green. | 2004 |
|
| Treatment of ichthyophthiriasis after malachite green. I. Concrete tanks at salmonid farms. | 2005 Apr 6 |
|
| Inhibition of human plasma cholinesterase by malachite green and related triarylmethane dyes: mechanistic implications. | 2005 Aug 15 |
|
| Treatment of ichthyophthiriasis after malachite green. II. Earth ponds at salmonid farms. | 2005 Aug 9 |
|
| DNA damage and G2/M arrest in Syrian hamster embryo cells during Malachite green exposure are associated with elevated phosphorylation of ERK1 and JNK1. | 2005 Dec 18 |
|
| Decreased phosphoactive ERKs and JNKs in Malachite-green-transformed Syrian hamster embryo fibroblasts are associated with increased phosphoactive p38 kinase: possible therapeutic importance. | 2006 |
|
| Elevated phosphorylation of Chk1 and decreased phosphorylation of Chk2 are associated with abrogation of G2/M checkpoint control during transformation of Syrian hamster embryo (SHE) cells by Malachite green. | 2006 Jun 18 |
|
| Methemoglobinemia due to malachite green ingestion in a child. | 2008 Apr |
|
| Establishment of a transgenic yeast screening system for estrogenicity and identification of the anti-estrogenic activity of malachite green. | 2008 Dec 15 |
|
| Inhibition of electric eel acetylcholinesterase by triarylmethane dyes. | 2008 Sep 25 |
|
| Disrupting actions of bisphenol A and malachite green on growth hormone receptor gene expression and signal transduction in seabream. | 2010 Jun |
|
| Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels. | 2011 May 1 |
|
| Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study. | 2015 May |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 07:55:15 UTC 2023
by
admin
on
Sat Dec 16 07:55:15 UTC 2023
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| Record UNII |
7G5QXS453J
|
| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID6044301
Created by
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4333500
Created by
admin on Sat Dec 16 07:55:15 UTC 2023 , Edited by admin on Sat Dec 16 07:55:15 UTC 2023
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25738-40-3
Created by
admin on Sat Dec 16 07:55:15 UTC 2023 , Edited by admin on Sat Dec 16 07:55:15 UTC 2023
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7G5QXS453J
Created by
admin on Sat Dec 16 07:55:15 UTC 2023 , Edited by admin on Sat Dec 16 07:55:15 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |
