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Details

Stereochemistry ACHIRAL
Molecular Formula C4H5NS
Molecular Weight 99.154
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-METHYLTHIAZOLE

SMILES

CC1=NC=CS1

InChI

InChIKey=VZWOXDYRBDIHMA-UHFFFAOYSA-N
InChI=1S/C4H5NS/c1-4-5-2-3-6-4/h2-3H,1H3

HIDE SMILES / InChI

Molecular Formula C4H5NS
Molecular Weight 99.154
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Enhanced nuclear delivery and cytotoxic activity of hydroxycamptothecin using o/w emulsions.
2007
Interleukin-6 protects cerebellar granule neurons from NMDA-induced neurotoxicity.
2007 Apr 25
Proinsecticide candidates N-(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl derivatives of imidacloprid and 1-chlorothiazolylmethyl-2-nitroimino-imidazolidine.
2007 Aug 15
Synthesis and identification of [1,2,4]thiadiazole derivatives as a new series of potent and orally active dual agonists of peroxisome proliferator-activated receptors alpha and delta.
2007 Aug 9
[Cytotoxicity of MTA, Dycal and GIC on human periodontal ligament cells in vitro].
2007 Dec
Biomimetic coating of compound titania and hydroxyapatite on titanium.
2007 Dec 15
Effect of cysteine and cystine addition on sensory profile and potent odorants of extruded potato snacks.
2007 Jul 11
Combined effect of bis-beta-chloroethylamine estrogen derivatives and doxorubicin on proliferation of sensitive and resistant MCF-7 cells.
2007 Mar
Decreased T cell response to mitogen and increased anti-cytoplasmic antibody in drug-free schizophrenic patients.
2007 Mar
Gamma-secretase inhibitors exerts antitumor activity via down-regulation of Notch and Nuclear factor kappa B in human tongue carcinoma cells.
2007 Nov
In vitro effect of oligo-hydroxyalkanoates on the growth of mouse fibroblast cell line L929.
2007 Sep
[Study on inhibitory effects of matrix metalloproteinase inhibitor on migration of cultured human lens epithelial cells].
2008 Apr
Osteo-promoting activity of OSTEOPLANT ANGIOSTAD in vitro.
2008 Apr
Mycophenolate mofetil prevents lethal acute liver failure in mice induced by bacille Calmette-Guérin and lipopolysaccharide.
2008 Apr
The use of isolated human lymphocytes in mycotoxin cytotoxicity testing.
2008 Aug
The expression and role of stromal cell-derived factor-1alpha-CXCR4 axis in human dental pulp.
2008 Aug
Characterization of porous poly(D,L-lactic-co-glycolic acid) sponges fabricated by supercritical CO2 gas-foaming method as a scaffold for three-dimensional growth of Hep3B cells.
2008 Aug 1
Concise assembly of highly substituted furan-fused 1,4-thiazepines and their Diels-Alder reactions with benzynes.
2008 Jan 18
ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo.
2008 Jul 23
RNAi depletion of deoxycytidine and deoxyguanosine kinase in human leukemic CEM cells.
2008 Jun
Modification of bone graft by blending with lecithin to improve hydrophilicity and biocompatibility.
2008 Mar
Synthesis and structure-activity relationships of thiadiazole-derivatives as potent and orally active peroxisome proliferator-activated receptors alpha/delta dual agonists.
2008 Mar 15
Potential use of hirudin in diabetic cataract: a study of galactose mediated human lens epithelial cells injury.
2008 May 28
Identification of CD133-positive radioresistant cells in atypical teratoid/rhabdoid tumor.
2008 May 7
Study on the biocompatibility of novel terpolyester poly(3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate).
2008 Nov
Human saphenous vein organ culture under controlled hemodynamic conditions.
2008 Oct
Tipifarnib in the treatment of newly diagnosed acute myelogenous leukemia.
2008 Sep
In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens.
2008 Sep
Mepacrine antagonises tumour cell growth induced by natural polyamines.
2008 Sep-Oct
Standardization of a colorimetric method to quantify growth and metabolic activity of Wolbachia-infected mosquito cells.
2008 Sep-Oct
Proliferative effects of Chishao on Schwann cells are FGF-uPA, and ERK- and JNK-dependent.
2009
Targeting CD24 for treatment of ovarian cancer by short hairpin RNA.
2009
Effects of three diterpenoids on tumour cell proliferation and telomerase activity.
2009
Ibuprofen augments bilirubin toxicity in rat cortical neuronal culture.
2009 Apr
Integrin-linked kinase is involved in lactoferrin-induced anchorage-independent cell growth and survival in PC12 cells.
2009 Apr 10
[Anti-inflammatory effect of near-infrared irradiated cell culture media].
2009 Aug
Surface modification on silicon with chitosan and biological research.
2009 Aug
Inhibition of multi-drug resistance of ovarian carcinoma by small interfering RNA targeting to MRP2 gene.
2009 Feb
Mechanisms of cytotoxicity of nickel ions based on gene expression profiles.
2009 Jan
A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients.
2009 Jan
c-Met-targeted RNA interference inhibits growth and metastasis of glioma U251 cells in vitro.
2009 Jun
Sparing methylation of beta-cyclodextrin mitigates cytotoxicity and permeability induction in respiratory epithelial cell layers in vitro.
2009 Jun 5
Protective effect of hydroxytyrosol against acrylamide-induced cytotoxicity and DNA damage in HepG2 cells.
2009 May 12
Intracellular GSH and ROS levels may be related to galactose-mediated human lens epithelial cell apoptosis: role of recombinant hirudin variant III.
2009 May 15
Inhibition of ameloblastoma invasion in vitro and in vivo by inhibitor of metalloproteinase-2 activity.
2009 Oct
Effect of implant surface microtopography on proliferation, neurotrophin secretion, and gene expression of Schwann cells.
2010 Apr
Photodynamic properties of ZnTPPS(4), ClAlPcS(2) and ALA in human melanoma G361 cells.
2010 Feb
Electrospun collagen-chitosan nanofiber: a biomimetic extracellular matrix for endothelial cell and smooth muscle cell.
2010 Feb
Osteogenic responses to different concentrations/ratios of BMP-2 and bFGF in bone formation.
2010 Jan
Neurotropin inhibits both capsaicin-induced substance P release and nerve growth factor-induced neurite outgrowth in cultured rat dorsal root ganglion neurones.
2010 Jan
Substance Class Chemical
Created
by admin
on Sat Dec 16 01:19:38 GMT 2023
Edited
by admin
on Sat Dec 16 01:19:38 GMT 2023
Record UNII
7G081N1ERP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2-METHYLTHIAZOLE
Systematic Name English
THIAZOLE, 2-METHYL-
Systematic Name English
2-METHYL-1,3-THIAZOLE
Systematic Name English
Code System Code Type Description
ECHA (EC/EINECS)
222-702-8
Created by admin on Sat Dec 16 01:19:38 GMT 2023 , Edited by admin on Sat Dec 16 01:19:38 GMT 2023
PRIMARY
FDA UNII
7G081N1ERP
Created by admin on Sat Dec 16 01:19:38 GMT 2023 , Edited by admin on Sat Dec 16 01:19:38 GMT 2023
PRIMARY
CAS
3581-87-1
Created by admin on Sat Dec 16 01:19:38 GMT 2023 , Edited by admin on Sat Dec 16 01:19:38 GMT 2023
PRIMARY
EPA CompTox
DTXSID20189346
Created by admin on Sat Dec 16 01:19:38 GMT 2023 , Edited by admin on Sat Dec 16 01:19:38 GMT 2023
PRIMARY
PUBCHEM
77129
Created by admin on Sat Dec 16 01:19:38 GMT 2023 , Edited by admin on Sat Dec 16 01:19:38 GMT 2023
PRIMARY