U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 15:33:58 GMT 2023
Edited
by admin
on Sat Dec 16 15:33:58 GMT 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Parvoviridae
Organism Genus Dependoparvovirus
Organism Species adeno-associated dependoparvovirus a
Infraspecific Type SUBSTRAIN
Infraspecific Name AAVrh.10- AAV2/ITR-CAG-SGSH-bovine hGH polyA
Part WHOLE
Record UNII
7DU50HR4GB
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OLENASUFLIGENE RELDUPARVOVEC
INN  
Official Name English
DNA (RECOMBINANT ADENO-ASSOCIATED VIRUS 2 VECTOR LYS-SAF302 HUMAN N-SULFOGLUCOSAMINE SULFOHYDROLASE CDNA-SPECIFYING)
Common Name English
SRP-9002
Code English
LYS-SAF-302
Code English
LYS-SAF302
Common Name English
AAVRH10-HSGSH
Common Name English
A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS SEROTYPE RH.10 (AAVRH.10) VECTOR, COMPRISED OF A RECOMBINANT GENOME WITH THE AAV2 INVERTED TERMINAL REPEATS (ITR) PACKAGED INTO AN AAVRH.10 CAPSID, EXPRESSING THE HUMAN N-SULFOGLUCOSAMINE SULFOHYDROLAS
Common Name English
olenasufligene relduparvovec [INN]
Common Name English
Code System Code Type Description
INN
10878
Created by admin on Sat Dec 16 15:33:58 GMT 2023 , Edited by admin on Sat Dec 16 15:33:58 GMT 2023
PRIMARY
FDA UNII
7DU50HR4GB
Created by admin on Sat Dec 16 15:33:58 GMT 2023 , Edited by admin on Sat Dec 16 15:33:58 GMT 2023
PRIMARY
NCI_THESAURUS
C175174
Created by admin on Sat Dec 16 15:33:58 GMT 2023 , Edited by admin on Sat Dec 16 15:33:58 GMT 2023
PRIMARY
CAS
2096510-84-6
Created by admin on Sat Dec 16 15:33:58 GMT 2023 , Edited by admin on Sat Dec 16 15:33:58 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
INSERTED GENE EXPRESSION VECTOR OLENASUFLIGENE RELDUPARVOVEC TRANSGENE INSERT R6L0YL1NNC
VECTOR EXPRESSED PROTEIN UNSPECIFIED SUBSTANCE
b094f9ee
(not in database)