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Details

Stereochemistry ACHIRAL
Molecular Formula C5H13FNO.Cl
Molecular Weight 156.617
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUOROCHOLINE CHLORIDE F-18

SMILES

[Cl-].C[N+](C)(C[18F])CCO

InChI

InChIKey=QJEHIIJVWXGJAB-ZZCPHWBCSA-M
InChI=1S/C5H13FNO.ClH/c1-7(2,5-6)3-4-8;/h8H,3-5H2,1-2H3;1H/q+1;/p-1/i6-1;

HIDE SMILES / InChI

Molecular Formula C5H12FNO
Molecular Weight 120.1558
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Fluorocholine-F18 is a tracer for positron emission tomography that can be used in oncology for the evaluation of metastatic prostate cancer, hepatocellular carcinoma, and recurrent brain tumor. After crossing the cell membrane by a carrier-mediated mechanism, Fluorocholine-F18 is converted to cytidinediphosphatecholine and incorporated into phosphatidylcholine which is a component of the cell membrane. This process has been found to be upregulated in malignant cells, providing a mechanism for the enhanced accumulation of radiolabelled choline by neoplasms.

Approval Year

Patents

Patents

Sample Use Guides

Adult dosage for I.V. injection 200 - 500 MBq
Route of Administration: Intravenous
Substance Class Chemical
Created
by admin
on Sat Dec 16 14:46:09 UTC 2023
Edited
by admin
on Sat Dec 16 14:46:09 UTC 2023
Record UNII
7DKH3NEJ7F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLUOROCHOLINE CHLORIDE F-18
Common Name English
(18F)-CHOLINE CHLORIDE
Common Name English
Fluorocholine (18f) chloride [WHO-DD]
Common Name English
ETHANAMINIUM, N-(FLUORO-18F-METHYL)-2-HYDROXY-N,N-DIMETHYL-, CHLORIDE (1:1)
Systematic Name English
FLUOROCHOLINE (18F) CHLORIDE
Common Name English
Code System Code Type Description
CAS
371173-14-7
Created by admin on Sat Dec 16 14:46:09 UTC 2023 , Edited by admin on Sat Dec 16 14:46:09 UTC 2023
PRIMARY
FDA UNII
7DKH3NEJ7F
Created by admin on Sat Dec 16 14:46:09 UTC 2023 , Edited by admin on Sat Dec 16 14:46:09 UTC 2023
PRIMARY
SMS_ID
100000170743
Created by admin on Sat Dec 16 14:46:09 UTC 2023 , Edited by admin on Sat Dec 16 14:46:09 UTC 2023
PRIMARY
PUBCHEM
134694270
Created by admin on Sat Dec 16 14:46:09 UTC 2023 , Edited by admin on Sat Dec 16 14:46:09 UTC 2023
PRIMARY
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