Azerutamig

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:26:34 GMT 2025` Edited by `admin` on `Wed Apr 02 00:26:34 GMT 2025`
Protein Type	TRISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN, HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	7DGR11S93X
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Azerutamig

Official Name

English

DF-1001

Preferred Name

English

DF1001

Code

English

azerutamig [INN]

Common Name

English

Immunoglobulin (H-gamma1_L-kappa)_scFvkh-H-gamma1(h-CH2-CH3), anti-[Homo sapiens KLRK1 (killer cell lectin like receptor K1, NKG2D, KLR, NKG2-D, CD314)] and anti-[Homo sapiens ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase er

Common Name

English

Heterodimeric multi-specific IgG1 antibody targeting human epidermal growth factor receptor 2 (HER2) and NKG2D on natural killer (NK) and cytotoxic T-cells

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

844121

Created by admin on Wed Apr 02 00:26:34 GMT 2025 , Edited by admin on Wed Apr 02 00:26:34 GMT 2025

Code System Code Type Description

FDA UNII

7DGR11S93X

Created by admin on Wed Apr 02 00:26:34 GMT 2025 , Edited by admin on Wed Apr 02 00:26:34 GMT 2025

PRIMARY

INN

13130

Created by admin on Wed Apr 02 00:26:34 GMT 2025 , Edited by admin on Wed Apr 02 00:26:34 GMT 2025

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NCI_THESAURUS

C172279

Created by admin on Wed Apr 02 00:26:34 GMT 2025 , Edited by admin on Wed Apr 02 00:26:34 GMT 2025

PRIMARY

CAS

2920336-42-9

Created by admin on Wed Apr 02 00:26:34 GMT 2025 , Edited by admin on Wed Apr 02 00:26:34 GMT 2025

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SMS_ID

300000024272

Created by admin on Wed Apr 02 00:26:34 GMT 2025 , Edited by admin on Wed Apr 02 00:26:34 GMT 2025

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From	To
1_23	1_88
1_100	1_171
1_149	1_223
1_255	2_231
1_258	2_234
1_290	1_350
1_383	2_354
1_396	1_454
2_22	2_96
2_149	2_205
2_225	3_214
2_266	2_326
2_372	2_430
3_23	3_88
3_134	3_194

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_326
N	2_302

Related Record Type Details


					7DGR11S93X

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL