Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C19H19N7O5 |
| Molecular Weight | 425.3981 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C2N=C(NC(=O)C3=CN=C(N)N=C3)N4CCN=C4C2=CC=C1OCCC(O)=O
InChI
InChIKey=KLKBHUCDAFIIPT-UHFFFAOYSA-N
InChI=1S/C19H19N7O5/c1-30-15-12(31-7-4-13(27)28)3-2-11-14(15)24-19(26-6-5-21-16(11)26)25-17(29)10-8-22-18(20)23-9-10/h2-3,8-9H,4-7H2,1H3,(H,27,28)(H2,20,22,23)(H,24,25,29)
| Molecular Formula | C19H19N7O5 |
| Molecular Weight | 425.3981 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 14:08:28 GMT 2023
by
admin
on
Sat Dec 16 14:08:28 GMT 2023
|
| Record UNII |
7D3BZM3BQN
|
| Record Status |
Validated (UNII)
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| Record Version |
|
-
Download
| Name | Type | Language | ||
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Systematic Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
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7D3BZM3BQN
Created by
admin on Sat Dec 16 14:08:28 GMT 2023 , Edited by admin on Sat Dec 16 14:08:28 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> METABOLITE |
The six healthy male volunteers received a single i.v. infusion of 12 mg copanlisib (2.76 MBq (14C)copanlisib) in a total volume of 40 mL as a 1-h infusion in the morning, 1-h after a light breakfast. 5 Caucasians and 1 Asian with an age 54.8 +/- 5.2 yeas (mean +/- SD, range: 47-61 years) and a BMI of 24.8 kg/m^2. Non-smokers and reported at the most light alcohol use.
AMOUNT EXCRETED
FECAL
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