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Details

Stereochemistry ACHIRAL
Molecular Formula C10H24N2
Molecular Weight 172.311
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TETRAMETHYLHEXAMETHYLENEDIAMINE

SMILES

CN(C)CCCCCCN(C)C

InChI

InChIKey=TXXWBTOATXBWDR-UHFFFAOYSA-N
InChI=1S/C10H24N2/c1-11(2)9-7-5-6-8-10-12(3)4/h5-10H2,1-4H3

HIDE SMILES / InChI
Molecular Formula C10H24N2
Molecular Weight 172.311
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Tetramethylhexamethylenediamine (6,3-ionene) is a Hexanediamine derivative patented by Abbott Laboratories. U.S.A. as heparin neutralizer. Heparin is anionic polymer and positively charged Tetramethylhexamethylenediamine, prevents its anticoagulant action. The antagonistic capacity would be due to the PEC formation between the ionene and heparin. Tetramethylhexamethylenediamine can also be used as an antispasmolytic drug.

Originator

v. Braun, J.
1
Sources: Berichte der Deutschen Chemischen Gesellschaft (1911), 43, 2853-64.

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
[Chemiluminescence of peritoneal macrophages activated by non-natural polyelectrolytes].
1985-05-01
Patents

Patents

WO9009405
1
Substance Class Chemical
Created
by admin
on Mon Mar 31 20:49:37 GMT 2025
Edited
by admin
on Mon Mar 31 20:49:37 GMT 2025
Record UNII
7D0T53S99V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
U-CAT 1000
Preferred Name English
TETRAMETHYLHEXAMETHYLENEDIAMINE
Systematic Name English
HEXAMETHYLENEBIS(DIMETHYLAMINE)
Systematic Name English
N,N,N',N'-TETRAMETHYL-1,6-HEXAMETHYLENEDIAMINE
Common Name English
1,6-HEXANEDIAMINE, N1,N1,N6,N6-TETRAMETHYL-
Systematic Name English
N,N,N',N'-TETRAMETHYLHEXAMETHYLENEDIAMINE
Systematic Name English
1,6-BIS(DIMETHYLAMINO)HEXANE
Systematic Name English
1,1,8,8-TETRAMETHYL-1,8-DIAZAOCTANE
Systematic Name English
1,6-HEXANEDIAMINE, N,N,N',N'-TETRAMETHYL-
Systematic Name English
Code System Code Type Description
FDA UNII
7D0T53S99V
Created by admin on Mon Mar 31 20:49:37 GMT 2025 , Edited by admin on Mon Mar 31 20:49:37 GMT 2025
PRIMARY
EPA CompTox
DTXSID5033701
Created by admin on Mon Mar 31 20:49:37 GMT 2025 , Edited by admin on Mon Mar 31 20:49:37 GMT 2025
PRIMARY
ECHA (EC/EINECS)
203-842-9
Created by admin on Mon Mar 31 20:49:37 GMT 2025 , Edited by admin on Mon Mar 31 20:49:37 GMT 2025
PRIMARY
CAS
111-18-2
Created by admin on Mon Mar 31 20:49:37 GMT 2025 , Edited by admin on Mon Mar 31 20:49:37 GMT 2025
PRIMARY
PUBCHEM
8097
Created by admin on Mon Mar 31 20:49:37 GMT 2025 , Edited by admin on Mon Mar 31 20:49:37 GMT 2025
PRIMARY
NIH
NCATS
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