5-Fluorowillardiine, (S)-

N[C@@H](CN1C=C(F)C(=O)NC1=O)C(O)=O

InChIKey=DBWPFHJYSTVBCZ-BYPYZUCNSA-N

InChI=1S/C7H8FN3O4/c8-3-1-11(2-4(9)6(13)14)7(15)10-5(3)12/h1,4H,2,9H2,(H,13,14)(H,10,12,15)/t4-/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Targets

Primary Target	Pharmacology	Potency
Glutamate receptor ionotropic, AMPA 1 9 Target ID: CHEMBL2009 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9226415\|https://www.ncbi.nlm.nih.gov/pubmed/15448189\|https://www.ncbi.nlm.nih.gov/pubmed/10854736\|https://www.ncbi.nlm.nih.gov/pubmed/10611433	Agonist 2678	14.7 nM [Ki]
Glutamate receptor ionotropic, AMPA 2 6 Target ID: CHEMBL4016 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9357531	Agonist 2678	25.1 nM [Ki]
Glutamate receptor ionotropic, AMPA 1 9 Target ID: CHEMBL2009 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20096591 \| https://www.ncbi.nlm.nih.gov/pubmed/7566471 \| https://www.ncbi.nlm.nih.gov/pubmed/9357531	Agonist 2678	380.0 nM [EC50]
Glutamate receptor ionotropic, AMPA 2 6 Target ID: CHEMBL4016 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20096591 \| https://www.ncbi.nlm.nih.gov/pubmed/7566471 \| https://www.ncbi.nlm.nih.gov/pubmed/9357531	Agonist 2678	463.0 nM [EC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:41:56 GMT 2023` Edited by `admin` on `Sat Dec 16 09:41:56 GMT 2023`
Record UNII	7CTR2LWV5M
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

5-Fluorowillardiine, (S)-

Common Name

English

(S)-(-)-5-FLUOROWILLARDINE

Common Name

English

(αS)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid

Systematic Name

English

(2S)-2-Amino-3-(5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid

Systematic Name

English

(5S)-Fluorowillardiine

Common Name

English

1(2H)-Pyrimidinepropanoic acid, α-amino-5-fluoro-3,4-dihydro-2,4-dioxo-, (αS)-

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID1042609