3-NITRO-L-TYROSINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H10N2O5
Molecular Weight	226.1861
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N[C@@H](CC1=CC=C(O)C(=C1)[N+]([O-])=O)C(O)=O

InChI

InChIKey=FBTSQILOGYXGMD-LURJTMIESA-N

InChI=1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14)/t6-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C9H10N2O5
Molecular Weight	226.1861
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Nitration of tyrosine residues in protein-nucleic acid complexes.	2001	11357592
In vitro production of peroxynitrite by haemocytes from marine bivalves: C-ELISA determination of 3-nitrotyrosine level in plasma proteins from Mytilus galloprovincialis and Crassostrea gigas.	2001	11231884
Adenosine triphosphate-dependent degradation of a fluorescent lambda N substrate mimic by Lon protease.	2001 Apr 1	11262158
Evidence for reactive nitrogen species formation in the gingivomucosal tissue.	2001 Feb	11332535
Inhibition of peroxynitrite-induced dityrosine formation with oxidized and reduced thiols, nitric oxide donors, and purine derivatives.	2001 Feb	11291595
Relation of oxidative protein damage and nitrotyrosine levels in the aging rat brain.	2001 Feb	11226738
Oxidative-stress-dependent up-regulation of Bcl-2 expression in the central nervous system of aged Fisher-344 rats.	2001 Feb	11181830
N-methyl-D-aspartate receptor antagonist reduces nitrotyrosine formation in caudate-putamen in rat focal cerebral ischemia-reperfusion.	2001 Feb 16	11166962
Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes.	2001 Jan	11208728
Expression of nitric oxide synthases and nitrotyrosine during blood-brain barrier breakdown and repair after cold injury.	2001 Jan	11204272
Beneficial effects of tempol, a membrane-permeable radical scavenger, on the multiple organ failure induced by zymosan in the rat.	2001 Jan	11176168
No evidence of NO-induced damage in potential donor organs after brain death.	2001 Jan	11166614
Antisense oligodeoxynucleotide to inducible nitric oxide synthase protects against transient focal cerebral ischemia-induced brain injury.	2001 Jan	11149663
Reduced severity of oxygen-induced retinopathy in eNOS-deficient mice.	2001 Jan	11133872
Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase.	2001 Jan	11133496
Reactive oxygen and nitrogen metabolites modulate fibronectin-induced fibroblast migration in vitro.	2001 Jan 1	11134892
Studies on a single immunoglobulin-binding domain of protein L from Peptostreptococcus magnus: the role of tyrosine-53 in the reaction with human IgG.	2001 Jan 15	11139405
Increased nitric oxide metabolites in exhaled breath condensate after exposure to tobacco smoke.	2001 Jun	11359961
Differential expression of nitric oxide synthases in bacterial meningitis: role of the inducible isoform for blood-brain barrier breakdown.	2001 Jun 15	11372027
Role of reactive nitrogen species in neuronal cell damage during intestinal schistosomiasis.	2001 Mar	11320648
Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat.	2001 Mar	11259502
Aging-related expression of inducible nitric oxide synthase and markers of tissue damage in the rat penis.	2001 Mar	11207215
Peroxynitrite inhibits inducible (type 2) nitric oxide synthase in murine lung epithelial cells in vitro.	2001 May 1	11316578
Acute cardiac allograft rejection in nitric oxide synthase-2(-/-) and nitric oxide synthase-2(+/+) mice: effects of cellular chimeras on myocardial inflammation and cardiomyocyte damage and apoptosis.	2001 May 22	11369694
Nitrotyrosination contributes minimally to toxicity of mutant SOD1 associated with ALS.	2001 May 8	11338199

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:50:56 GMT 2023` Edited by `admin` on `Fri Dec 15 18:50:56 GMT 2023`
Record UNII	7COY1HA6HK
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

3-NITRO-L-TYROSINE

Systematic Name

English

(2S)-2-AMINO-3-(4-HYDROXY-3-NITROPHENYL)PROPANOIC ACID

Systematic Name

English

NITROTYROSINE

Systematic Name

English

NSC-37413

Code

English

TYROSINE, 3-NITRO-, L-

Systematic Name

English

3-NITROTYROSINE

Systematic Name

English

L-TYROSINE, 3-NITRO-

Systematic Name

English

NITRATED TYROSINE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C73539