Efitazanamivir alfa

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 10:56:05 GMT 2025` Edited by `admin` on `Wed Apr 02 10:56:05 GMT 2025`
Protein Type	FC PROTEIN
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	7CA5JND7QE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

84-329-Immunoglobulin G1 [135-tyrosine,137-threonine,139-glutamic acid] (human ?1-chain constant region), dimer, N6-[15-[4-[20-carboxy-14-[2-[2-(carboxymethylamino)ethoxy]ethyl]-2,5,8,11,17-pentaoxa-14,20-diazaheneicos-1-yl]-1H-1,2,3-triazol-1-yl]-1-oxo-

Preferred Name

English

Efitazanamivir alfa

Official Name

English

efitazanamivir alfa [INN]

Common Name

English

Fc fragment of human immunoglobulin G1 (1-247) [Homo sapiens IGHG1*01(CH1 final 15 residues (1-15), hinge (16-30), CH2 M52>Y, S54>T, T56>E (31-140), CH3 (141-245), CHS (246-247))], dimer (26-26':29-29')-bisdisulfide, prod

Common Name

English

Code System Code Type Description

FDA UNII

7CA5JND7QE

Created by admin on Wed Apr 02 10:56:05 GMT 2025 , Edited by admin on Wed Apr 02 10:56:05 GMT 2025

PRIMARY

CAS

2781830-14-4

Created by admin on Wed Apr 02 10:56:05 GMT 2025 , Edited by admin on Wed Apr 02 10:56:05 GMT 2025

PRIMARY

INN

13066

Created by admin on Wed Apr 02 10:56:05 GMT 2025 , Edited by admin on Wed Apr 02 10:56:05 GMT 2025

PRIMARY

From	To
2_167	2_225
2_61	2_121
1_167	1_225
1_61	1_121
1_29	2_29
1_26	2_26

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_97
N	2_97

Related Record Type Details


					L6O3XI777I

ZANAMIVIR

CONJUGATE COMPONENT->CONJUGATE

Amount:

Related Record Type Details


					7CA5JND7QE

Efitazanamivir alfa

ACTIVE MOIETY

Comments:

neuraminidase inhibitor, antiviral

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_5] [1_13] [1_18] [1_46] [1_117] [1_126] [1_134] [1_192] [2_5] [2_13] [2_18] [2_46] [2_117] [2_126] [2_134] [2_192]	SITE_SPECIFIC	K	Amount:	UNSPECIFIED SUBSTANCE	f470c93d (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL