GLAUCINE HYDROBROMIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H25NO4.BrH
Molecular Weight	436.339
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Br.[H][C@]12CC3=CC(OC)=C(OC)C=C3C4=C1C(CCN2C)=CC(OC)=C4OC

InChI

InChIKey=DFFLCVRJWUOGPN-RSAXXLAASA-N

InChI=1S/C21H25NO4.BrH/c1-22-7-6-12-9-18(25-4)21(26-5)20-14-11-17(24-3)16(23-2)10-13(14)8-15(22)19(12)20;/h9-11,15H,6-8H2,1-5H3;1H/t15-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C21H25NO4
Molecular Weight	355.4275
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Objective evaluation of dextromethorphan and glaucine as antitussive agents.	1984 May	6375709
Central action of glaucine in rodents.	1994	7863789
Antipoliovirus structure-activity relationships of some aporphine alkaloids.	1998 Apr	9584402
Geographic distribution of three alkaloid chemotypes of Croton lechleri.	2002 Jun	12088421
Antifungal activity of the methanolic extract and alkaloids of Glaucium oxylobum.	2003 Jul	12837370
The efficient synthesis of morphinandienone alkaloids by using a combination of hypervalent iodine(III) reagent and heteropoly acid.	2004 Oct 11	15372696
Photostability and photoprotection factor of boldine and glaucine.	2005 Jul 1	15963438
A novel alkaloid from Mitrephora maingayi.	2005 Jun	15938142
Structure-affinity relationships of halogenated predicentrine and glaucine derivatives at D1 and D2 dopaminergic receptors: halogenation and D1 receptor selectivity.	2005 Jun 1	15862999
Identification and quantification of isoquinoline alkaloids in the genus Sarcocapnos by GC-MS.	2005 Sep-Oct	16223088
[Acute glaucine syndrome in the physician's practice: the clinical picture and potential danger].	2006	17243616
Antihyperglycemic effect of aporphines and their derivatives in normal and diabetic rats.	2006 Oct	16924583
Cardiovascular toxicity associated with recreational use of diphenylprolinol (diphenyl-2-pyrrolidinemethanol [D2PM]).	2008 Sep	18821489
Amino acid derivatives of aporphinic alkaloid glaucine and their antioxidant activity.	2009	19400187
Ascorbic acid and tetrahydrobiopterin potentiate the EDHF phenomenon by generating hydrogen peroxide.	2009 Nov 1	19592567
The antinociceptive and anti-inflammatory activities of caulerpin, a bisindole alkaloid isolated from seaweeds of the genus Caulerpa.	2009 Nov 26	20098607
Alkaloids from Glaucium flavum from Sardinia.	2010 Jul	20552526
Screening of antinociceptive components in Corydalis yanhusuo W.T. Wang by comprehensive two-dimensional liquid chromatography/tandem mass spectrometry.	2010 Mar	20101504

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:28:26 GMT 2023` Edited by `admin` on `Sat Dec 16 01:28:26 GMT 2023`
Record UNII	7BPY1SMR1C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GLAUCINE HYDROBROMIDE

Common Name

English

4H-DIBENZO(DE,G)QUINOLINE, 5,6,6A,7-TETRAHYDRO-1,2,9,10-TETRAMETHOXY-6-METHYL-, HYDROBROMIDE (1:1), (6AS)-

Systematic Name

English

GLAUCINE HYDROBROMIDE, (+)-

Common Name

English

GLAUCINE HYDROBROMIDE [MI]

Common Name

English

(6AS)-5,6,6A,7-TETRAHYDRO-1,2,9,10-TETRAMETHOXY-6-METHYL-4H-DIBENZO(DE,G)QUINOLINE HYDROBROMIDE

Common Name

English

Glaucine hydrobromide [WHO-DD]

Common Name

English

(+)-GLAUCINE HYDROBROMIDE

Common Name

English

Code System Code Type Description

MERCK INDEX

m5741