BUTETAMATE HYDROCHLORIDE

Cl.CCC(C(=O)OCCN(CC)CC)C1=CC=CC=C1

InChIKey=SRIJBBUJJSYXHB-UHFFFAOYSA-N

InChI=1S/C16H25NO2.ClH/c1-4-15(14-10-8-7-9-11-14)16(18)19-13-12-17(5-2)6-3;/h7-11,15H,4-6,12-13H2,1-3H3;1H

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Butetamate is a cough suppressant. It exerts antispasmodic, bronchodilator and anticholinergic properties.

Targets

Primary Target	Pharmacology	Condition	Potency
acetylcholine receptor activity 5 Target ID: GO:0015464 Sources: http://www.laboratorio-ariston.com.ar/productos/wp-content/uploads/Heliphenicol-1.pdf	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Cough 106 Sources: http://www.laboratorio-ariston.com.ar/productos/wp-content/uploads/Heliphenicol-1.pdf	Primary		Approved 8429	HELIPHENICOL Approved Use Acute cough due to variety of causes, especially dry cough, suppression of preoperative and postoperative cough in surgery and bronchoscopy. whooping cough.

In Vivo Use Guide

Solution containing 3 mg/ml butetamate citrate. Children: 1 ml/kg/day. Adults: 10 ml every 6 hours.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:04:48 GMT 2023` Edited by `admin` on `Sat Dec 16 11:04:48 GMT 2023`
Record UNII	7B4VN4QC7H
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

BUTETAMATE HYDROCHLORIDE

Common Name

English

BENZENEACETIC ACID, .ALPHA.-ETHYL-, 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE (1:1)

Systematic Name

English

Code System Code Type Description

CAS

15533-77-4