AVOPLACEL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 05:51:06 GMT 2025` Edited by `admin` on `Wed Apr 02 05:51:06 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	ALLOGENIC HUMAN
Source Materials State	LIVE
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Part	placenta
Fraction Material Type	cells
Fraction Name	mesenchymal-like adherent stromal cells
Record UNII	79NT7I8J0C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AVOPLACEL

Official Name

English

HUMAN CULTURE EXPANDED ALLOGENIC MESENCHYMAL-LIKE ADHERENT STROMAL CELLS FOR CELL-BASED THERAPY. CELLS ARE OF FETAL ORIGIN AND DERIVED FROM PLACENTAE OF HEALTHY DONORS FOLLOWING A CESAREAN SECTION. CELLS EXPRESS CELL SURFACE MARKERS CD29, CD73, AND CD105

Preferred Name

English

AVOPLACEL [USAN]

Common Name

English

avoplacel [INN]

Common Name

English

Code System Code Type Description

FDA UNII

79NT7I8J0C

Created by admin on Wed Apr 02 05:51:06 GMT 2025 , Edited by admin on Wed Apr 02 05:51:06 GMT 2025

PRIMARY

SMS_ID

100000183405

Created by admin on Wed Apr 02 05:51:06 GMT 2025 , Edited by admin on Wed Apr 02 05:51:06 GMT 2025

PRIMARY

NCI_THESAURUS

C171652

Created by admin on Wed Apr 02 05:51:06 GMT 2025 , Edited by admin on Wed Apr 02 05:51:06 GMT 2025

PRIMARY

INN

10883

Created by admin on Wed Apr 02 05:51:06 GMT 2025 , Edited by admin on Wed Apr 02 05:51:06 GMT 2025

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USAN

HI-182

Created by admin on Wed Apr 02 05:51:06 GMT 2025 , Edited by admin on Wed Apr 02 05:51:06 GMT 2025

PRIMARY

Related Record Type Details


					79NT7I8J0C

AVOPLACEL

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
PROTEIN EXPRESSED	BIOLOGICAL		`4O4QWG0B3C` HUMAN INTERLEUKIN-6

PROTEIN EXPRESSED	BIOLOGICAL		`PC30892LX5` INTERLEUKIN-8

PROTEIN EXPRESSED	BIOLOGICAL		`17I3DH51XQ` C-C MOTIF CHEMOKINE 2

ANTIGEN EXPRESSED	BIOLOGICAL		`J4GH02V4K5` INTEGRIN BETA-1

ANTIGEN EXPRESSED	BIOLOGICAL		`T8635M4C7O` 5'-NUCLEOTIDASE

ANTIGEN EXPRESSED	BIOLOGICAL		`1Y8Q34P575` ENDOGLIN