U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Thu Jul 06 17:18:03 UTC 2023
Edited
by admin
on Thu Jul 06 17:18:03 UTC 2023
Protein Type RECEPTOR
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
79AAW649HW
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SUBSTANCE-K RECEPTOR
Common Name English
NKNAR
Common Name English
TAC2R
Common Name English
NK-2 RECEPTOR
Common Name English
TACHYKININ RECEPTOR 2
Common Name English
SKR
Common Name English
NK2R
Common Name English
NEUROKININ A RECEPTOR
Common Name English
NK-2R
Common Name English
Code System Code Type Description
FDA UNII
79AAW649HW
Created by admin on Thu Jul 06 17:18:04 UTC 2023 , Edited by admin on Thu Jul 06 17:18:04 UTC 2023
PRIMARY
UNIPROT
P21452
Created by admin on Thu Jul 06 17:18:04 UTC 2023 , Edited by admin on Thu Jul 06 17:18:04 UTC 2023
PRIMARY
PHAROS
P21452
Created by admin on Thu Jul 06 17:18:04 UTC 2023 , Edited by admin on Thu Jul 06 17:18:04 UTC 2023
PRIMARY
From To
1_106 1_181
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_11
N 1_19
Related Record Type Details
INHIBITOR->OFF-TARGET
Neratinib concentration at 10 microM
INHIBITOR
Percent inhibition of specific binding
INHIBITOR -> TARGET
Radioligand binding assay
BINDING
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Tachykinin NK2 receptor antagonist that was developed by Sanofi-Aventis for anti-depressant potential
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Ki
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL