Neldaleucel

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 21:05:58 GMT 2025` Edited by `admin` on `Wed Apr 02 21:05:58 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	AUTOLOGOUS HUMAN
Source Materials State	LIVE
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Part	blood
Fraction Name	cd56 depleted pbmc cells
Record UNII	78SU4N7MVG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MT-601

Preferred Name

English

Neldaleucel

Official Name

English

NELDALEUCEL [USAN]

Common Name

English

MT-601 is an autologous multi-tumor associated antigen (TAA)-specific T cell immunotherapy product that depending on the patient?s endogenous precursors recognizes cancer cells expressing at least one of the 6 TAAs via native T cell receptors (TCRs), whi

Common Name

English

Autologous multi (6) tumor-associated antigen (TAA)-specific T cell product that is specifically directed against the following six TAAs: preferentially expressed antigen in melanoma (PRAME), Wilms tumor 1 (WT1), New York esophageal 1 (NY-ESO-1), synovia

Common Name

English

Code System Code Type Description

SMS_ID

300000049640

Created by admin on Wed Apr 02 21:05:58 GMT 2025 , Edited by admin on Wed Apr 02 21:05:58 GMT 2025

PRIMARY

INN

13215

Created by admin on Wed Apr 02 21:05:58 GMT 2025 , Edited by admin on Wed Apr 02 21:05:58 GMT 2025

PRIMARY

FDA UNII

78SU4N7MVG

Created by admin on Wed Apr 02 21:05:58 GMT 2025 , Edited by admin on Wed Apr 02 21:05:58 GMT 2025

PRIMARY

NCI_THESAURUS

C200467

Created by admin on Wed Apr 02 21:05:58 GMT 2025 , Edited by admin on Wed Apr 02 21:05:58 GMT 2025

PRIMARY

USAN

LM-134

Created by admin on Wed Apr 02 21:05:58 GMT 2025 , Edited by admin on Wed Apr 02 21:05:58 GMT 2025

PRIMARY

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ACTIVE MOIETY

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
CULTURE	T CELL STIMULATION	BIOLOGICAL		WILMS TUMOR PROTEIN (1-15)	3HX5255USK
CULTURE	EXPANSION	BIOLOGICAL		INTERLEUKIN-12 HUMAN	7B590791ER
CULTURE	EXPANSION	BIOLOGICAL		HUMAN INTERLEUKIN-6	4O4QWG0B3C
CULTURE	T CELL STIMULATION	BIOLOGICAL		SURVIVIN	3AU321J2HF
CULTURE	T CELL STIMULATION	BIOLOGICAL		UNSPECIFIED SUBSTANCE	0f325b74
CULTURE	T CELL STIMULATION	BIOLOGICAL		MELANOMA-ASSOCIATED ANTIGEN 4	QV12MEH92G
CULTURE	T CELL STIMULATION	BIOLOGICAL		PRAME (1-15)	2JY898ER7K
CULTURE	EXPANSION	BIOLOGICAL		HUMAN IL-15	HRJ300HC9W
CULTURE	EXPANSION	BIOLOGICAL		INTERLEUKIN-7 HUMAN RECOMBINANT	418XB47Y71
CULTURE	T CELL STIMULATION	BIOLOGICAL		PROTEIN SSX2	QRD4YDY9BR