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Details

Stereochemistry ACHIRAL
Molecular Formula C16H21ClN4
Molecular Weight 304.818
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ENPIPRAZOLE

SMILES

CN1C=C(CCN2CCN(CC2)C3=CC=CC=C3Cl)C=N1

InChI

InChIKey=WBFVWQJVMMIQFI-UHFFFAOYSA-N
InChI=1S/C16H21ClN4/c1-19-13-14(12-18-19)6-7-20-8-10-21(11-9-20)16-5-3-2-4-15(16)17/h2-5,12-13H,6-11H2,1H3

HIDE SMILES / InChI

Molecular Formula C16H21ClN4
Molecular Weight 304.818
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Enpiprazole is a heterocyclic three-ringed pyrazolylalkyl piperazine derivative. Enpiprazole has a cataleptic action very similar to that of neuroleptics, and its effect on muscle relaxation is comparable with that of diazepam. Enpiprazole exerts anxiolytic properties in animals.

CNS Activity

Curator's Comment: Enpiprazole is CNS active in animals. No human data available.

Approval Year

PubMed

PubMed

TitleDatePubMed
Action of enpiprazole on emotional behavior induced by hypothalamic stimulation in rats and cats.
1976 Sep 29
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:16:03 GMT 2023
Edited
by admin
on Sat Dec 16 16:16:03 GMT 2023
Record UNII
78G92X9EH7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ENPIPRAZOLE
INN   WHO-DD  
INN  
Official Name English
Enpiprazole [WHO-DD]
Common Name English
enpiprazole [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C28197
Created by admin on Sat Dec 16 16:16:03 GMT 2023 , Edited by admin on Sat Dec 16 16:16:03 GMT 2023
Code System Code Type Description
CAS
31729-24-5
Created by admin on Sat Dec 16 16:16:03 GMT 2023 , Edited by admin on Sat Dec 16 16:16:03 GMT 2023
PRIMARY
FDA UNII
78G92X9EH7
Created by admin on Sat Dec 16 16:16:03 GMT 2023 , Edited by admin on Sat Dec 16 16:16:03 GMT 2023
PRIMARY
NCI_THESAURUS
C73208
Created by admin on Sat Dec 16 16:16:03 GMT 2023 , Edited by admin on Sat Dec 16 16:16:03 GMT 2023
PRIMARY
SMS_ID
100000080256
Created by admin on Sat Dec 16 16:16:03 GMT 2023 , Edited by admin on Sat Dec 16 16:16:03 GMT 2023
PRIMARY
EVMPD
SUB06544MIG
Created by admin on Sat Dec 16 16:16:03 GMT 2023 , Edited by admin on Sat Dec 16 16:16:03 GMT 2023
PRIMARY
INN
2960
Created by admin on Sat Dec 16 16:16:03 GMT 2023 , Edited by admin on Sat Dec 16 16:16:03 GMT 2023
PRIMARY
EPA CompTox
DTXSID30865609
Created by admin on Sat Dec 16 16:16:03 GMT 2023 , Edited by admin on Sat Dec 16 16:16:03 GMT 2023
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PUBCHEM
208921
Created by admin on Sat Dec 16 16:16:03 GMT 2023 , Edited by admin on Sat Dec 16 16:16:03 GMT 2023
PRIMARY
WIKIPEDIA
Enpiprazole
Created by admin on Sat Dec 16 16:16:03 GMT 2023 , Edited by admin on Sat Dec 16 16:16:03 GMT 2023
PRIMARY
ChEMBL
CHEMBL2104269
Created by admin on Sat Dec 16 16:16:03 GMT 2023 , Edited by admin on Sat Dec 16 16:16:03 GMT 2023
PRIMARY
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SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY