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Details

Stereochemistry ACHIRAL
Molecular Formula Cu.2NO3
Molecular Weight 187.9396
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CUPRIC NITRATE CU-64

SMILES

[64Cu++].[O-][N+]([O-])=O.[O-][N+]([O-])=O

InChI

InChIKey=XTVVROIMIGLXTD-GLJCYROLSA-N
InChI=1S/Cu.2NO3/c;2*2-1(3)4/q+2;2*-1/i1+0;;

HIDE SMILES / InChI

Molecular Formula NO3
Molecular Weight 62.0049
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Cu
Molecular Weight 63.9298
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Cu-64 is an isotope of copper with potential use in PET imaging and the targeted radiotherapy of cancer. It has a complex decay scheme, with electron capture, beta-emission and positron emission branches. Cu-64 in the most simple salt form as well as linked to a variety of bioactive molecules can be used as theranostic agents in human malignancies such as prostate, glioblastoma, melanoma, breast cancers) and also diagnosis of human copper-associated diseases such as atherosclerosis, Alzheimer’s etc. There are some examples of investigational Cu-64-based radiopharmaceuticals: Cu-64-ATSM for imaging hypoxia, Cu-64-labeled peptides for tumor-receptor targeting, Cu-64-labeled monoclonal antibodies for targeting tumor antigens, and Cu-64-labeled nanoparticles for cancer targeting.

Approval Year

PubMed

PubMed

TitleDatePubMed
Copper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research.
2009 Aug
Molecular imaging of cancer with copper-64 radiopharmaceuticals and positron emission tomography (PET).
2009 Jul 21
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:04:22 GMT 2023
Edited
by admin
on Sat Dec 16 08:04:22 GMT 2023
Record UNII
78FG8ZV38N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CUPRIC NITRATE CU-64
Common Name English
COPPER CU-64 NITRATE
Common Name English
COPPER NITRATE CU-64
Common Name English
COPPER DINITRATE CU-64
Common Name English
CUPRIC CU-64 NITRATE
Common Name English
Code System Code Type Description
PUBCHEM
92135702
Created by admin on Sat Dec 16 08:04:22 GMT 2023 , Edited by admin on Sat Dec 16 08:04:22 GMT 2023
PRIMARY
FDA UNII
78FG8ZV38N
Created by admin on Sat Dec 16 08:04:22 GMT 2023 , Edited by admin on Sat Dec 16 08:04:22 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY