COBALTOUS CHLORIDE CO-60

Details

Stereochemistry	ACHIRAL
Molecular Formula	2Cl.Co
Molecular Weight	130.84
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Cl-].[Cl-].[60Co++]

InChI

InChIKey=GVPFVAHMJGGAJG-FCHARDOESA-L

InChI=1S/2ClH.Co/h2*1H;/q;;+2/p-2/i;;1+1

HIDE SMILES / InChI

Molecular Formula	Co
Molecular Weight	59.9338
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/30616914 | https://www.ncbi.nlm.nih.gov/pubmed/27601951

Cobaltous chloride Co-60 is a gamma emitter used in nuclear medicine in the form of high specific activity sources. Co-60 brachytherapy is used to treat carcinoma of the uterine cervix, the second most common cancer in women and the most common cause of death in cancer patients in the developing countries. Co-60 high dose rate brachytherapy unit is a good choice especially for the centers with a small number of brachytherapy procedures. Co-60 demonstrates cost-favorability in Peru and may similarly in other locations.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
pernicious anemia 2 Sources: https://www.tabletwise.com/us/rubratope-60-capsule/uses-benefits-working	Diagnostic		Approved 8429	RUBRATOPE-60 Approved Use Unknown Launch Date 6.0220801E10
Cervical Cancer, Uterine 2

PubMed

Title	Date	PubMed
Gynecological brachytherapy for postoperative endometrial cancer: dosimetric analysis (Ir-192 vs Co-60).	2017 Nov	28516398
Cost in perspective: direct assessment of American market acceptability of Co-60 in gynecologic high-dose-rate brachytherapy and contrast with experience abroad.	2018 Dec	30662472
Dosimetric study of CO-60 source step size in uterine cervix intracavitary HDR brachytherapy.	2019 Mar-Apr	30616914

Sample Use Guides

In Vivo Use Guide

The retrospective study is based on data of 15 patients of carcinoma cervix (Ca-cx) treated with Co-60 high-dose-rate intracavitary brachytherapy with dose of 21 Gy in three fractions with source step size of 2.5 mm after external beam radiotherapy of 46 Gy.

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:50:29 UTC 2023` Edited by `admin` on `Fri Dec 15 15:50:29 UTC 2023`
Record UNII	7812FUQ8VK
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

COBALTOUS CHLORIDE CO-60

Common Name

English

RUBRATOPE-60 KIT COMPONENT COBALT CHLORIDE CO-60

Common Name

English

COBALT CHLORIDE CO-60 [ORANGE BOOK]

Common Name

English

COBALT CHLORIDE CO-60 COMPONENT OF RUBRATOPE-60 KIT

Common Name

English

COBALT CHLORIDE CO-60

Common Name

English

COBALT CHLORIDE, CO-60

Common Name

English

COBALT-60 DICHLORIDE

Common Name

English

Cobalt chloride (60CoCl2)

Common Name

English

COBALTOUS CHLORIDE CO 60 [USAN]

Common Name

English

COBALT CHLORIDE ((SUP 60)COCL2)

Common Name

English

COBALTOUS CHLORIDE CO 60

Official Name

English

COBALT CHLORIDE CO 60

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1446