Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H8N2O3 |
| Molecular Weight | 180.1607 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CNC(=O)C1=CC=CN=C1
InChI
InChIKey=ZBSGKPYXQINNGF-UHFFFAOYSA-N
InChI=1S/C8H8N2O3/c11-7(12)5-10-8(13)6-2-1-3-9-4-6/h1-4H,5H2,(H,10,13)(H,11,12)
| Molecular Formula | C8H8N2O3 |
| Molecular Weight | 180.1607 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Determination of nicacid and its metabolites in human plasma by HPLC-MS/MS]. | 2010-11 |
|
| Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study. | 2010-10 |
|
| Role of nicotinamide in DNA damage, mutagenesis, and DNA repair. | 2010-07-25 |
|
| A comparison of the pharmacokinetics of two different formulations of extended-release niacin. | 2009-01 |
|
| Targeting multiple dyslipidemias with fixed combinations--focus on extended release niacin and simvastatin. | 2008 |
|
| Analysis of time-related metabolic fluctuations induced by ethionine in the rat. | 2007-12 |
|
| The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet. | 2007-09 |
|
| Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation. | 2007-08 |
|
| Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites. | 2007-06 |
|
| Nicotinic acid induces secretion of prostaglandin D2 in human macrophages: an in vitro model of the niacin flush. | 2007-06 |
|
| Azabicyclic amino acids by stereoselective dearomatizing cyclization of the enolates of N-nicotinoyl glycine derivatives. | 2006-11-09 |
|
| Metabolite projection analysis for fast identification of metabolites in metabonomics. Application in an amiodarone study. | 2006-06-01 |
|
| Simultaneous determination of niacin, niacinamide and nicotinuric acid in human plasma. | 2005-01-04 |
|
| Simultaneous determination of nicotinic acid and its metabolites using hydrophilic interaction chromatography with tandem mass spectrometry. | 2005 |
|
| Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats. | 2004-01 |
|
| Synthesis and asymmetric reducing performance of chitin/dihydronicotinamide conjugates having glycine or L-leucine spacer arms. | 2002-07-09 |
|
| Simultaneous determination of nicotinic acid and its two metabolites in human plasma using solid-phase extraction in combination with high performance liquid chromatography. | 1993 |
|
| The bioavailability of sustained release nicotinic acid formulations. | 1991-10 |
|
| Comparison of excretion of nicotinuric acid after ingestion of two controlled release nicotinic acid preparations in man. | 1988-12 |
|
| High-performance liquid-chromatographic determination of free nicotinic acid and its metabolite, nicotinuric acid, in plasma and urine. | 1978-10 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:57:06 GMT 2025
by
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on
Mon Mar 31 18:57:06 GMT 2025
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| Record UNII |
77V5315PIU
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| Record Status |
Validated (UNII)
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77V5315PIU
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DTXSID50207022
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C002477
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71273
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77V5315PIU
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7563
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