(2-CHLOROPHENYL)DIPHENYLMETHANOL

OC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=C(Cl)C=CC=C3

InChIKey=KTVAHLGKTSPDOG-UHFFFAOYSA-N

InChI=1S/C19H15ClO/c20-18-14-8-7-13-17(18)19(21,15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14,21H

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
calcium-activated potassium channel activity 3 Target ID: GO:0015269 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9151659 \| https://www.ncbi.nlm.nih.gov/pubmed/11181430	Inhibitor 8297
Slow afterhyperpolarization 1 Target ID: Slow afterhyperpolarization Sources: https://www.ncbi.nlm.nih.gov/pubmed/11181430	Inhibitor 8297	2.2 µM [IC50]
High voltage-activated (HVA) Ca2+ current 1 Target ID: High voltage-activated (HVA) Ca2+ current Sources: https://www.ncbi.nlm.nih.gov/pubmed/11181430	Inhibitor 8297	2.2 µM [IC50]

PubMed

Title	Date	PubMed
Production and characterization of hot-melt extruded films containing clotrimazole.	2003 Aug	12906333
Development and validation of HPLC method for determination of clotrimazole and its two degradation products in spray formulation.	2007 Sep 30	19073060
Influence of ionising irradiation on clotrimazole in the solid state.	2009 Nov 1	18930367
Space-filling trialkoxysilane: synthesis and self-assembly into low-density monolayers.	2010 Dec 21	21090761

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:09:32 GMT 2023` Edited by `admin` on `Sat Dec 16 09:09:32 GMT 2023`
Record UNII	77N69DJ59Q
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

(2-CHLOROPHENYL)DIPHENYLMETHANOL

Systematic Name

English

CLOTRIMAZOLE RELATED COMPOUND A [USP-RS]

Common Name

English

TRAM 3

Brand Name

English

O-CHLOROPHENYLDIPHENYLMETHANOL

Systematic Name

English

NSC-170882

Code

English

CLOTRIMAZOLE IMPURITY A [EP IMPURITY]

Common Name

English

BENZENEMETHANOL, 2-CHLORO-.ALPHA.,.ALPHA.-DIPHENYL-

Systematic Name

English

Code System Code Type Description

NSC

170882