VOLAGIDEMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 23:20:26 GMT 2025` Edited by `admin` on `Mon Mar 31 23:20:26 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG2
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	77JYS6UZ0M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VOLAGIDEMAB

Official Name

English

IMMUNOGLOBULIN G2, ANTI-(HUMAN GLUCAGON RECEPTOR) (HUMAN MONOCLONAL REMD 477 .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL REMD 477 .KAPPA.-CHAIN, DIMER

Preferred Name

English

REMD-477

Code

English

IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS GCGR (GLUCAGON RECEPTOR)), HOMO SAPIENS MONOCLONAL ANTIBODYGAMMA2 HEAVY CHAIN HOMO SAPIENS (1-454) (VH (HOMO SAPIENS IGHV3-33*01 (95.9%)-(IGHD)-IGHJ1*01(90.9%)) (8.8.21) (1-128)-HOMO SAPIENS IGHG2*01 (CH1 (129-

Systematic Name

English

AMG-477

Code

English

VOLAGIDEMAB [USAN]

Common Name

English

volagidemab [INN]

Common Name

English

Code System Code Type Description

FDA UNII

77JYS6UZ0M

Created by admin on Mon Mar 31 23:20:26 GMT 2025 , Edited by admin on Mon Mar 31 23:20:26 GMT 2025

PRIMARY

NCI_THESAURUS

C167005

Created by admin on Mon Mar 31 23:20:26 GMT 2025 , Edited by admin on Mon Mar 31 23:20:26 GMT 2025

PRIMARY

USAN

GH-31

Created by admin on Mon Mar 31 23:20:26 GMT 2025 , Edited by admin on Mon Mar 31 23:20:26 GMT 2025

PRIMARY

INN

10989

Created by admin on Mon Mar 31 23:20:26 GMT 2025 , Edited by admin on Mon Mar 31 23:20:26 GMT 2025

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CAS

1233956-13-2

Created by admin on Mon Mar 31 23:20:26 GMT 2025 , Edited by admin on Mon Mar 31 23:20:26 GMT 2025

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SMS_ID

300000005884

Created by admin on Mon Mar 31 23:20:26 GMT 2025 , Edited by admin on Mon Mar 31 23:20:26 GMT 2025

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From	To
1_22	1_96
1_155	1_211
1_268	1_328
1_374	1_432
3_23	3_88
3_134	3_194
1_142	3_214
2_22	2_96
2_155	2_211
2_268	2_328
2_374	2_432
4_23	4_88
4_134	4_194
2_142	4_214
1_230	2_230
1_231	2_231
1_234	2_234
1_237	2_237

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_304
N	2_304

Related Record Type Details


					G2BWF9H576

GLUCAGON RECEPTOR

TARGET -> INHIBITOR

Related Record Type Details


					77JYS6UZ0M

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL