U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 10:35:04 GMT 2023
Edited
by admin
on Sat Dec 16 10:35:04 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
77JYS6UZ0M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VOLAGIDEMAB
INN  
Official Name English
REMD-477
Code English
IMMUNOGLOBULIN G2, ANTI-(HUMAN GLUCAGON RECEPTOR) (HUMAN MONOCLONAL REMD 477 .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL REMD 477 .KAPPA.-CHAIN, DIMER
Systematic Name English
IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS GCGR (GLUCAGON RECEPTOR)), HOMO SAPIENS MONOCLONAL ANTIBODYGAMMA2 HEAVY CHAIN HOMO SAPIENS (1-454) (VH (HOMO SAPIENS IGHV3-33*01 (95.9%)-(IGHD)-IGHJ1*01(90.9%)) (8.8.21) (1-128)-HOMO SAPIENS IGHG2*01 (CH1 (129-
Systematic Name English
AMG-477
Code English
VOLAGIDEMAB [USAN]
Common Name English
volagidemab [INN]
Common Name English
Code System Code Type Description
FDA UNII
77JYS6UZ0M
Created by admin on Sat Dec 16 10:35:04 GMT 2023 , Edited by admin on Sat Dec 16 10:35:04 GMT 2023
PRIMARY
NCI_THESAURUS
C167005
Created by admin on Sat Dec 16 10:35:04 GMT 2023 , Edited by admin on Sat Dec 16 10:35:04 GMT 2023
PRIMARY
USAN
GH-31
Created by admin on Sat Dec 16 10:35:04 GMT 2023 , Edited by admin on Sat Dec 16 10:35:04 GMT 2023
PRIMARY
INN
10989
Created by admin on Sat Dec 16 10:35:04 GMT 2023 , Edited by admin on Sat Dec 16 10:35:04 GMT 2023
PRIMARY
CAS
1233956-13-2
Created by admin on Sat Dec 16 10:35:04 GMT 2023 , Edited by admin on Sat Dec 16 10:35:04 GMT 2023
PRIMARY
From To
1_22 1_96
1_155 1_211
1_268 1_328
1_374 1_432
3_23 3_88
3_134 3_194
1_142 3_214
2_22 2_96
2_155 2_211
2_268 2_328
2_374 2_432
4_23 4_88
4_134 4_194
2_142 4_214
1_230 2_230
1_231 2_231
1_234 2_234
1_237 2_237
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_304
N 2_304
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL