Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C4H7NO2 |
| Molecular Weight | 101.1039 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1CCN1
InChI
InChIKey=IADUEWIQBXOCDZ-UHFFFAOYSA-N
InChI=1S/C4H7NO2/c6-4(7)3-1-2-5-3/h3,5H,1-2H2,(H,6,7)
| Molecular Formula | C4H7NO2 |
| Molecular Weight | 101.1039 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The application of the yeast N-acetyltransferase MPR1 gene and the proline analogue L-azetidine-2-carboxylic acid as a selectable marker system for plant transformation. | 2010-06 |
|
| Heterologous expression of Saccharomyces cerevisiae MPR1 gene confers tolerance to ethanol and L: -azetidine-2-carboxylic acid in Hansenula polymorpha. | 2010-02 |
|
| Synthesis and evaluation of new endomorphin analogues modified at the Pro(2) residue. | 2009-08-01 |
|
| Engineering of the yeast antioxidant enzyme Mpr1 for enhanced activity and stability. | 2009-06-01 |
|
| Engineering of the yeast ubiquitin ligase Rsp5: isolation of a new variant that induces constitutive inactivation of the general amino acid permease Gap1. | 2009-02 |
|
| Azetidine-2-carboxylic acid in the food chain. | 2009-01 |
|
| The discovery of BMAA, and examples of biomagnification and protein incorporation involving other non-protein amino acids. | 2009 |
|
| Actions of a proline analogue, L-thiazolidine-4-carboxylic acid (T4C), on Trypanosoma cruzi. | 2009 |
|
| Misincorporation of the proline analog azetidine-2-carboxylic acid in the pathogenesis of multiple sclerosis: a hypothesis. | 2008-11 |
|
| Identification of amino acid residues essential for the yeast N-acetyltransferase Mpr1 activity by site-directed mutagenesis. | 2008-06 |
|
| A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery. | 2008-04-10 |
|
| Azetidine-derived amino acids versus proline derivatives. alternative trends in reverse turn induction. | 2008-03-07 |
|
| Azetidine-2-carboxylic acid in garden beets (Beta vulgaris). | 2006-05 |
|
| The special five-membered ring of proline: An experimental and theoretical investigation of alkali metal cation interactions with proline and its four- and six-membered ring analogues. | 2006-03-23 |
|
| Distinct yet linked: chaperone networks in the eukaryotic cytosol. | 2006 |
|
| Practical asymmetric preparation of azetidine-2-carboxylic acid. | 2005-10-28 |
|
| Efficient route to (S)-azetidine-2-carboxylic acid. | 2005-10 |
|
| Substrate specificity and functional characterisation of the H+/amino acid transporter rat PAT2 (Slc36a2). | 2005-01 |
|
| Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the proline leads to a high rate of uncoupled 2-oxoglutarate decarboxylation. | 2004-12-31 |
|
| Azetidine-induced accumulation of class I small heat shock proteins in the soluble fraction provides thermotolerance in soybean seedlings. | 2004-12 |
|
| Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress. | 2004-11-26 |
|
| Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.). | 2004-11 |
|
| Expression of a novel yeast gene that detoxifies the proline analog azetidine-2-carboxylate confers resistance during tobacco seed germination, callus and shoot formation. | 2004-03 |
|
| Four permeases import proline and the toxic proline analogue azetidine-2-carboxylate into yeast. | 2004-02 |
|
| Characterization of novel acetyltransferases found in budding and fission yeasts that detoxify a proline analogue, azetidine-2-carboxylic acid. | 2003-01 |
|
| Structure-activity relationships of dynorphin analogs substituted in positions 2 and 3. | 2003 |
|
| Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae. | 2002-11-22 |
|
| Proline residues at the C terminus of nascent chains induce SsrA tagging during translation termination. | 2002-09-13 |
|
| Differential expression of two stress-inducible hsp70 genes by various stressors. | 2002-05-31 |
|
| A novel acetyltransferase found in Saccharomyces cerevisiae Sigma1278b that detoxifies a proline analogue, azetidine-2-carboxylic acid. | 2001-11-09 |
|
| Coinduction of two low-molecular-weight stress proteins, alpha B crystallin and HSP28, by heat or arsenite stress in human glioma cells. | 1993-11 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:05:13 GMT 2025
by
admin
on
Mon Mar 31 23:05:13 GMT 2025
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| Record UNII |
775261TI36
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| Record Status |
Validated (UNII)
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| Record Version |
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775261TI36
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DTXSID80859699
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219-740-2
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2517-04-6
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m2171
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17288
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