Maridebart

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 07:21:49 GMT 2025` Edited by `admin` on `Wed Apr 02 07:21:49 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	76AFN9QO5H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Immunoglobulin G1, anti-(glucose-dependent insulinotropic polypeptide receptor) [275-cysteine,295-cysteine,300-glycine,305-cysteine] (human ?1-chain), disulfide with human ?-chain, dimer

Preferred Name

English

Maridebart

Official Name

English

gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-33*01 (92.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, G1v64 CH2 C36, G1v54-30 CH2 C83, G8

Common Name

English

maridebart [INN]

Common Name

English

Code System Code Type Description

INN

12601

Created by admin on Wed Apr 02 07:21:49 GMT 2025 , Edited by admin on Wed Apr 02 07:21:49 GMT 2025

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FDA UNII

76AFN9QO5H

Created by admin on Wed Apr 02 07:21:49 GMT 2025 , Edited by admin on Wed Apr 02 07:21:49 GMT 2025

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NCI_THESAURUS

C199070

Created by admin on Wed Apr 02 07:21:49 GMT 2025 , Edited by admin on Wed Apr 02 07:21:49 GMT 2025

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SMS_ID

300000053750

Created by admin on Wed Apr 02 07:21:49 GMT 2025 , Edited by admin on Wed Apr 02 07:21:49 GMT 2025

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CAS

2761478-99-1

Created by admin on Wed Apr 02 07:21:49 GMT 2025 , Edited by admin on Wed Apr 02 07:21:49 GMT 2025

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From	To
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
2_370	2_428
2_295	2_305
2_264	2_324
2_223	4_214
1_223	3_214
2_147	2_203
2_22	2_96
1_370	1_428
1_295	1_305
1_264	1_324
1_232	2_232
1_229	2_229
1_147	1_203
1_22	1_96

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	SITE_SPECIFIC			PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_450] [2_450]	C-TERMINUS		Amount:	LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL