Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H19O2PS2 |
| Molecular Weight | 242.339 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCSP(=O)(OCC)SCCC
InChI
InChIKey=VJYFKVYYMZPMAB-UHFFFAOYSA-N
InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3
| Molecular Formula | C8H19O2PS2 |
| Molecular Weight | 242.339 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Ethoprophos is a broad-spectrum nematicide and insecticide used pre-planting to control nematodes and soil dwelling insects. Research and testing has shown ethoprophos to offer effective control for soil nematodes and insects when used according to label guidelines. Ethoprophos is a cholinesterase inhibitor.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Parameterisation, evaluation and comparison of pesticide leaching models to data from a Bologna field site, Italy. | 2003 Jan |
|
| Degradation of ethoprophos in three physicochemically different soils treated with composted manure and chemical fertilizer. | 2003 Mar |
|
| Predicting and measuring environmental concentration of pesticides in air after soil application. | 2003 Sep-Oct |
|
| The enhanced biodegradation of fenamiphos in soils from previously treated sites and the effect of soil fumigants. | 2004 Sep |
|
| Biological monitoring use in refining the exposure assessment of agricultural operators. | 2005 |
|
| Prediction of pesticide volatilization with PELMO 3.31. | 2005 Jul |
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| Determination of pesticides by solid phase extraction followed by gas chromatography with nitrogen-phosphorous detection in natural water and comparison with solvent drop microextraction. | 2006 Feb |
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| Parallel assessment of male reproductive function in workers and wild rats exposed to pesticides in banana plantations in Guadeloupe. | 2008 Jul 30 |
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| Companion animals as sentinels for community exposure to industrial chemicals: the Fairburn, GA, propyl mercaptan case study. | 2008 May-Jun |
|
| Multi-walled carbon nanotubes as efficient solid-phase extraction materials of organophosphorus pesticides from apple, grape, orange and pineapple fruit juices. | 2008 Nov 21 |
|
| Longitudinal trends in organophosphate incidents reported to the National Pesticide Information Center, 1995-2007. | 2009 Apr 20 |
|
| Multivariate analysis of toxicological and environmental properties of soil nematicides. | 2009 Jan |
Patents
Sample Use Guides
In an in vivo cytogenetic study, groups of male Sprague-Dawley rats were treated orally with technical ethoprophos (95.7 percent) at 0, 2, 9 or 20 mg/kg b.w./day for five consecutive days. The animals were given colchicine i.p. at 4 mg/kg b.w. four hours after the last dose and then sacrificed two hours later for metaphase analysis of bone marrow cells. There was no significant difference between control and treated groups in the incidence of bone marrow cells with chromosomal aberrations.
Route of Administration:
Oral
In Vitro Use Guide
Curator's Comment: Ethoprophos concentration of 400 ug/L caused a ChE inhibition by 79%. https://www.ncbi.nlm.nih.gov/pubmed/22458230
Ethoprophos, at the non-toxic concentrations ranging from 2.5 to 25 nl/ml, did not induce a detectable level of unscheduled DNA synthesis in primary rat hepatocytes in vitro.
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 17:19:19 UTC 2023
by
admin
on
Fri Dec 15 17:19:19 UTC 2023
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| Record UNII |
765Y5683OQ
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| Record Status |
Validated (UNII)
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| Record Version |
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EPA PESTICIDE CODE |
41101
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C474843
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765Y5683OQ
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236-152-1
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ethoprophos
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38665
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m5069
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C001182
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82035
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3289
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ETHOPROP
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DTXSID4032611
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13194-48-4
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