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Details

Stereochemistry ACHIRAL
Molecular Formula C8H19O2PS2
Molecular Weight 242.339
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ETHOPROPHOS

SMILES

CCCSP(=O)(OCC)SCCC

InChI

InChIKey=VJYFKVYYMZPMAB-UHFFFAOYSA-N
InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3

HIDE SMILES / InChI

Molecular Formula C8H19O2PS2
Molecular Weight 242.339
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Ethoprophos is a broad-spectrum nematicide and insecticide used pre-planting to control nematodes and soil dwelling insects. Research and testing has shown ethoprophos to offer effective control for soil nematodes and insects when used according to label guidelines. Ethoprophos is a cholinesterase inhibitor.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
In an in vivo cytogenetic study, groups of male Sprague-Dawley rats were treated orally with technical ethoprophos (95.7 percent) at 0, 2, 9 or 20 mg/kg b.w./day for five consecutive days. The animals were given colchicine i.p. at 4 mg/kg b.w. four hours after the last dose and then sacrificed two hours later for metaphase analysis of bone marrow cells. There was no significant difference between control and treated groups in the incidence of bone marrow cells with chromosomal aberrations.
Route of Administration: Oral
In Vitro Use Guide
Ethoprophos, at the non-toxic concentrations ranging from 2.5 to 25 nl/ml, did not induce a detectable level of unscheduled DNA synthesis in primary rat hepatocytes in vitro.
Substance Class Chemical
Record UNII
765Y5683OQ
Record Status Validated (UNII)
Record Version