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Details

Stereochemistry ACHIRAL
Molecular Formula 2C2H3O2.Co.4H2O
Molecular Weight 249.0824
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of COBALTOUS ACETATE TETRAHYDRATE

SMILES

O.O.O.O.[Co++].CC([O-])=O.CC([O-])=O

InChI

InChIKey=ZBYYWKJVSFHYJL-UHFFFAOYSA-L
InChI=1S/2C2H4O2.Co.4H2O/c2*1-2(3)4;;;;;/h2*1H3,(H,3,4);;4*1H2/q;;+2;;;;/p-2

HIDE SMILES / InChI

Molecular Formula Co
Molecular Weight 58.933195
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C2H4O2
Molecular Weight 60.052
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Cobalt is a transition metal, naturally ocurring in the minerals cobaltite, smaltite, and erythrite, and is often associated with nickel, silver, lead, copper, and iron ores, from which it is most frequently obtained as a by-product. Depending on the considered species, cobalt has multiple industrial applications including the production of alloys and hard metal, diamond polishing, drying agents, pigments and catalysts. Cobalt is an essential component of Vitamin B12 (hydroxycolalamin). Cobalt functions as a co-factor in enzyme catalysed reactions and is involved in the production of erythropoietin, a hormone that stimulates the formation of erythrocytes. Cobalt salts were used to treat anemia and stimulate erythropoiesis, but was withdrawn from market since Co(II) cations are genotoxic in vitro and in vivo, and carcinogenic in rodents. Hovewer, Co salts are reported to be used by athletes as a doping

Originator

Curator's Comment: Cobalt was discovered by Georg Brandt, a Swedish chemist, in 1739.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: Q9NWT6
Gene ID: 55662.0
Gene Symbol: HIF1AN
Target Organism: Homo sapiens (Human)
1.0 µM [Ki]
Conditions
PubMed

PubMed

TitleDatePubMed
Erythropoietic effect of cobalt in patients with or without anemia.
1949 May 12
Carcinogenic sulfide salts of nickel and cadmium induce H2O2 formation by human polymorphonuclear leukocytes.
1990 Dec 1
Cobalt and antimony: genotoxicity and carcinogenicity.
2003 Dec 10
Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway.
2005 Aug
Synthesis and antifungal potential of Co(II) complexes of 1-(2'-hydroxyphenyl) ethylideneanilines.
2006 Feb
In vitro assessment of cobalt oxide particle toxicity: identifying and circumventing interference.
2013 Sep
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:39:22 GMT 2025
Edited
by admin
on Mon Mar 31 18:39:22 GMT 2025
Record UNII
7648Z91O1N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BIS(ACETATO)TETRAAQUOCOBALT
Preferred Name English
COBALTOUS ACETATE TETRAHYDRATE
MI  
Common Name English
COBALTOUS ACETATE TETRAHYDRATE [MI]
Common Name English
COBALT ACETATE TETRAHYDRATE
Systematic Name English
COBALT DIACETATE TETRAHYDRATE
Systematic Name English
COBALT(II) ACETATE TETRAHYDRATE
Systematic Name English
Code System Code Type Description
PUBCHEM
61372
Created by admin on Mon Mar 31 18:39:22 GMT 2025 , Edited by admin on Mon Mar 31 18:39:22 GMT 2025
PRIMARY
MERCK INDEX
m3687
Created by admin on Mon Mar 31 18:39:22 GMT 2025 , Edited by admin on Mon Mar 31 18:39:22 GMT 2025
PRIMARY Merck Index
CAS
6147-53-1
Created by admin on Mon Mar 31 18:39:22 GMT 2025 , Edited by admin on Mon Mar 31 18:39:22 GMT 2025
PRIMARY
FDA UNII
7648Z91O1N
Created by admin on Mon Mar 31 18:39:22 GMT 2025 , Edited by admin on Mon Mar 31 18:39:22 GMT 2025
PRIMARY
SMS_ID
300000053196
Created by admin on Mon Mar 31 18:39:22 GMT 2025 , Edited by admin on Mon Mar 31 18:39:22 GMT 2025
PRIMARY
EPA CompTox
DTXSID80210423
Created by admin on Mon Mar 31 18:39:22 GMT 2025 , Edited by admin on Mon Mar 31 18:39:22 GMT 2025
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE
PARENT -> SALT/SOLVATE