Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H7O4P |
| Molecular Weight | 174.0911 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OP(O)(=O)OC1=CC=CC=C1
InChI
InChIKey=CMPQUABWPXYYSH-UHFFFAOYSA-N
InChI=1S/C6H7O4P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H,(H2,7,8,9)
| Molecular Formula | C6H7O4P |
| Molecular Weight | 174.0911 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Disodium phenyl phosphate is a monophenyl ester of phosphoric acid. It is used as tool compound to study the efficacy of phosphatases. Hydrolysis of phenyl phosphate by milk phosphatases was used to used to indicate whether milk has been adequately pasteurized or whether it has been contaminated with raw milk after pasteurization. Phenyl phosphate was also used as a molecular fragment for fragment-based drug discovery of Src SH2.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Continuous assay for acid phosphatase using phenyl phosphate. | 1996 Oct 15 |
|
| Cooperative kinetics of human prostatic acid phosphatase. | 2001 Aug 13 |
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| Purification and characterization of banana fruit acid phosphatase. | 2001 Dec |
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| Elaboration and characterization of spatially controlled assemblies of complementary polyphenol oxidase-alkaline phosphatase activities on electrodes. | 2001 Jul 1 |
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| Cloning and characterization of a second acid phosphatase from Sinorhizobium meliloti strain 104A14. | 2001 Oct |
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| Alkaline phosphatase revisited: hydrolysis of alkyl phosphates. | 2002 Mar 5 |
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| Effects of some trivalent metal ions on the fluoride-induced chemiluminescence from a phenylphosphate-substituted dioxetane Lumigen PPD. | 2002 Sep-Oct |
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| Structure-based design of novel nonpeptide inhibitors of the Src SH2 domain:phosphotyrosine mimetics exploiting multifunctional group replacement chemistry. | 2003 |
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| Nature and mode of action of NAD and ATP dephosphorylating enzyme from Aspergillus terreus DSM 826. | 2003 |
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| Inhibition of beta-lactamases by monocyclic acyl phosph(on)ates. | 2003 Feb 18 |
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| A fluorescent sensor for 2,3-bisphosphoglycerate using a europium tetra-N-oxide bis-bipyridine complex for both binding and signaling purposes. | 2003 Jan 3 |
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| The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase. | 2003 May 7 |
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| Inhibitors for proteins endowed with catalytic and non-catalytic activity which recognize pTyr. | 2004 Oct |
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| Rapid and highly sensitive electrochemical determination of alkaline phosphatase using a composite tyrosinase biosensor. | 2005 Jan 15 |
|
| Thiolysis and alcoholysis of phosphate tri- and monoesters with alkyl and aryl leaving groups. An ab initio study in the gas phase. | 2005 Jun 30 |
|
| An 18 kDa acid phosphatase from chicken heart possesses phosphotransferase activity. | 2006 Feb |
|
| Urea-, thiourea-, and guanidine-linked glycooligomers as phosphate binders in water. | 2006 Jul 7 |
|
| Nano-titanium dioxide composites for the enrichment of phosphopeptides. | 2006 May 26 |
|
| Theoretical evaluation of the substrate-assisted catalysis mechanism for the hydrolysis of phosphate monoester dianions. | 2007 |
|
| Nanostructured progesterone immunosensor using a tyrosinase-colloidal gold-graphite-Teflon biosensor as amperometric transducer. | 2007 Jul 16 |
|
| A highly sensitive assay for monitoring the secretory pathway and ER stress. | 2007 Jun 27 |
|
| A review of current intravaginal drug delivery approaches employed for the prophylaxis of HIV/AIDS and prevention of sexually transmitted infections. | 2008 |
|
| Immobilization of enzymes through one-pot chemical preoxidation and electropolymerization of dithiols in enzyme-containing aqueous suspensions to develop biosensors with improved performance. | 2008 Aug 1 |
|
| Time-resolved fluorescence-based assay for the determination of alkaline phosphatase activity and application to the screening of its inhibitors. | 2008 Jan |
|
| A DFT study on the formation of a phosphohistidine intermediate in prostatic acid phosphatase. | 2008 Jul 30 |
|
| Determination of lactoferrin and immunoglobulin g in animal milks by new immunosensors. | 2009 |
|
| EEVD motif of heat shock cognate protein 70 contributes to bacterial uptake by trophoblast giant cells. | 2009 Dec 15 |
|
| [Comparative-enzymologic study of phosphatase activity of hydrobionts from Pacific Ocean]. | 2009 Jul-Aug |
|
| Enhanced bactericidal activity of enterocin AS-48 in combination with essential oils, natural bioactive compounds and chemical preservatives against Listeria monocytogenes in ready-to-eat salad. | 2009 Sep |
|
| Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models. | 2010 Aug 12 |
|
| Immobilization of enzymes at high load/activity by aqueous electrodeposition of enzyme-tethered chitosan for highly sensitive amperometric biosensing. | 2010 Aug 15 |
|
| Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets. | 2010 Dec 1 |
|
| Chemoprotective Effect of Sobatum against Lithium-Induced Oxidative Damage in Rats. | 2010 Jan |
|
| Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling. | 2010 Nov 10 |
Sample Use Guides
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:00:27 GMT 2023
by
admin
on
Fri Dec 15 18:00:27 GMT 2023
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| Record UNII |
75M88J863E
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| Record Status |
Validated (UNII)
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| Record Version |
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CFR |
21 CFR 176.170
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701-64-4
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75M88J863E
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DB03298
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DTXSID6044981
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12793
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211-857-7
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37548
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