U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:38:58 GMT 2023
Edited
by admin
on Sat Dec 16 13:38:58 GMT 2023
Protein Type SINGLE CHAIN ANTIBODY
Protein Sub Type BISPECIFIC T CELL ENGAGER
Record UNII
74X82ST8Q1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TARLATAMAB
USAN   INN  
Official Name English
AMG-757
Code English
IMMUNOGLOBULIN, ANTI-(HUMAN NOTCH LIGAND DLL3) (HUMAN MONOCLONAL DAELD-HWZV-1 SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSILON.-CHAIN) (HUMAN M
Common Name English
IMMUNOGLOBULIN SCFV-SCFV-SCFC, ANTI-(HOMO SAPIENS DLL3 (DELTA-LIKE LIGAND 3)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), MONOCLONAL ANTIBODY SINGLE CHAIN (SCFV)2-SCFC, BISPECIFIC; IG SINGLE CHAIN SCFV-SCFV-SCFC, ANTI-DLL3 AND ANTI-CD3E (1-982) (S
Common Name English
tarlatamab [INN]
Common Name English
TARLATAMAB [USAN]
Common Name English
IMMUNOGLOBULIN SCFV-SCFV-SCFC, ANTI-(HOMO SAPIENS DLL3 (DELTA-LIKE LIGAND 3)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), MONOCLONAL ANTIBODY SINGLE CHAIN (SCFV)2-SCFC, BISPECIFIC
Common Name English
Tarlatamab [WHO-DD]
Common Name English
AMG757
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 665418
Created by admin on Sat Dec 16 13:38:59 GMT 2023 , Edited by admin on Sat Dec 16 13:38:59 GMT 2023
Code System Code Type Description
FDA UNII
74X82ST8Q1
Created by admin on Sat Dec 16 13:38:59 GMT 2023 , Edited by admin on Sat Dec 16 13:38:59 GMT 2023
PRIMARY
INN
11420
Created by admin on Sat Dec 16 13:38:59 GMT 2023 , Edited by admin on Sat Dec 16 13:38:59 GMT 2023
PRIMARY
CAS
2307488-83-9
Created by admin on Sat Dec 16 13:38:59 GMT 2023 , Edited by admin on Sat Dec 16 13:38:59 GMT 2023
PRIMARY
NCI_THESAURUS
C175858
Created by admin on Sat Dec 16 13:38:59 GMT 2023 , Edited by admin on Sat Dec 16 13:38:59 GMT 2023
PRIMARY
USAN
JK-173
Created by admin on Sat Dec 16 13:38:59 GMT 2023 , Edited by admin on Sat Dec 16 13:38:59 GMT 2023
PRIMARY
From To
1_22 1_95
1_44 1_234
1_156 1_222
1_269 1_345
1_409 1_477
1_506 1_761
1_509 1_764
1_541 1_601
1_572 1_582
1_647 1_705
1_796 1_856
1_827 1_837
1_902 1_960
Related Record Type Details
TARGET -> ACTIVATOR
BINDING
Kd
TARGET -> ACTIVATOR
BINDING
Kd
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL