TUBULIN BETA CHAIN

Approval Year

Substance Class	Protein
Protein Sub Type
Record UNII	74UG0EWZ60
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TUBB5

Preferred Name

English

TUBULIN BETA CHAIN

Common Name

English

TUBULIN BETA-5 CHAIN

Common Name

English

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Code System

Code

Type

Description

FDA UNII

74UG0EWZ60

PRIMARY

UNIPROT

P07437

PRIMARY

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Subunit 0

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Glycosylation Link Type	Site
N	1_184
N	1_337
N	1_370

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Related Record

Type

Details


					WDT5V5OB9F

ABT-751

INHIBITOR -> TARGET

Comments:

Binds to the colchicine site on ?-tubulin that leads to a block in the cell cycle at the G2M phase, resulting in cellular apoptosis


					P88XT4IS4D

PACLITAXEL

LIGAND->TARGET

Amount:


					P14M0DWS2J

CEVIPABULIN

LIGAND->TARGET

Amount:


					Y7KSX9YI58

AVANBULIN

INHIBITOR OF AGGREGATION->TARGET

Comments:

DESTABILIZED TUBULIN POLYMERS

Amount:


					LB2951OCS5

FLAG-003 FREE BASE

LIGAND->TARGET

Comments:

binds to the colchicine-binding site on tubulin and interferes in microtubule processing.

Amount:

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	ESTIMATED 49700 Da (average)

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