Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C2H3FO2 |
| Molecular Weight | 77.045 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C[18F]
InChI
InChIKey=QEWYKACRFQMRMB-KTXUZGJCSA-N
InChI=1S/C2H3FO2/c3-1-2(4)5/h1H2,(H,4,5)/i3-1
| Molecular Formula | C2H3FO2 |
| Molecular Weight | 77.045 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Fluoroacetic acid F-18 (18F-Fluoroacetate,18F-FAC) is an analog of acetate with a longer radioactive half-life (18F=110 min). Fluoroacetic acid F-18 was under investigation as a PET imaging agent. 18F-FAC was considered a promising alternative to 11C-ACE for positron tomographic imaging of prostate cancer, and possibly of other neoplasms with relatively low glucose use.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Long-chain F-18 fatty acids for the study of regional metabolism in heart and liver; odd-even effects of metabolism in mice. | 1979 Nov |
|
| 18F-fluoroacetate: a potential acetate analog for prostate tumor imaging--in vivo evaluation of 18F-fluoroacetate versus 11C-acetate. | 2007 Mar |
|
| Evaluation of 6-([(18)F]fluoroacetamido)-1-hexanoicanilide for PET imaging of histone deacetylase in the baboon brain. | 2009 Apr |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 02:14:07 UTC 2023
by
admin
on
Sat Dec 16 02:14:07 UTC 2023
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| Record UNII |
74Q3U8O789
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID20226624
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450656
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74Q3U8O789
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DB15202
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7574-44-9
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| Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |
