PORPHOBILINOGEN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H14N2O4
Molecular Weight	226.2292
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

NCC1=C(CC(O)=O)C(CCC(O)=O)=CN1

InChI

InChIKey=QSHWIQZFGQKFMA-UHFFFAOYSA-N

InChI=1S/C10H14N2O4/c11-4-8-7(3-10(15)16)6(5-12-8)1-2-9(13)14/h5,12H,1-4,11H2,(H,13,14)(H,15,16)

HIDE SMILES / InChI

Molecular Formula	C10H14N2O4
Molecular Weight	226.2292
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

An acute attack may be precipitated by drugs affecting the liver, by infection and by diet. The discovery of porphobilinogen in urine is a critical value that can eliminate or reduce adverse effects from drugs or anesthetics.

Approval Year

PubMed

PubMed

Show entries

Title	Date	PubMed
Simultaneous determination of delta-aminolevulinic acid, porphobilinogen, levulinic acid and glycine in culture broth by capillary electrophoresis.	2001 Dec 14	11771832
Selenoxides inhibit delta-aminolevulinic acid dehydratase.	2001 Feb 3	11275419
The tolerability of newer immunosuppressive medications in a patient with acute intermittent porphyria.	2001 Jan	11144989
Is delta-aminolevulinic acid dehydratase rate limiting in heme biosynthesis following exposure of cells to delta-aminolevulinic acid?	2001 Mar	11281029
Variegate porphyria with coexistent decrease in porphobilinogen deaminase activity.	2001 Oct-Nov	11800145

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Substance Class	Chemical
Record UNII	74KHC72QXK
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

PORPHOBILINOGEN

Common Name

English

PORPHOBILINOGEN [MI]

Common Name

English

1H-PYRROLE-3-PROPANOIC ACID, 5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-

Systematic Name

English

3-(5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL)PROPANOIC ACID

Systematic Name

English

Showing 1 to 4 of 4 entries

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Classification Tree

Code System

Code

Urine

LOINC

34356-6

Urine

LOINC

2811-8

Subpart B--Clinical Chemistry Test Systems

CFR

21 CFR 862.1590

Urine

LOINC

14882-5

Urine

LOINC

12245-7

Showing 1 to 5 of 14 entries

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Code System

Code

Type

Description

EPA CompTox

DTXSID4060070

PRIMARY

CAS

487-90-1

PRIMARY

DRUG BANK

DB02272

PRIMARY

MERCK INDEX

m8991

PRIMARY

Merck Index

PUBCHEM

1021

PRIMARY

Showing 1 to 5 of 11 entries

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