U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:45:39 GMT 2023
Edited
by admin
on Sat Dec 16 15:45:39 GMT 2023
Protein Type FC FUSION PROTEIN
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
74D9ZOJ6IR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OMFILOCTOCOG ALFA
INN  
Official Name English
1-740-BLOOD COAGULATION FACTOR VIII (RECOMBINANT HUMAN SCT800 HEAVY CHAIN) FUSION PROTEIN WITH HUMAN BLOOD COAGULATION FACTOR VIII B DOMAIN FRAGMENT (14-AMINO ACID LINKER) FUSION PROTEIN WITH BLOOD COAGULATION FACTOR VIII (RECOMBINANT HUMAN SCT800 LIGHT
Common Name English
HUMAN COAGULATION FACTOR VIII (FVIII, ANTIHEMOPHILIC FACTOR, AHF, PROCOAGULANT COMPONENT) WITH DELETED B-DOMAIN (746-1639)-SEQUENCE: SINGLE-CHAIN RECOMBINANT FVIII COMPOSED OF DOMAINS A1-A1-A2-A2 (1-740), THE B-DOMAIN N-AND C-TERMINAL FRAGMENTS (741-745)
Common Name English
SCT800
Code English
omfiloctocog alfa [INN]
Common Name English
SCT-800
Code English
Code System Code Type Description
NCI_THESAURUS
C175177
Created by admin on Sat Dec 16 15:45:39 GMT 2023 , Edited by admin on Sat Dec 16 15:45:39 GMT 2023
PRIMARY
FDA UNII
74D9ZOJ6IR
Created by admin on Sat Dec 16 15:45:39 GMT 2023 , Edited by admin on Sat Dec 16 15:45:39 GMT 2023
PRIMARY
INN
11213
Created by admin on Sat Dec 16 15:45:39 GMT 2023 , Edited by admin on Sat Dec 16 15:45:39 GMT 2023
PRIMARY
CLINICAL_TRIALS.GOV
NCT02888223
Created by admin on Sat Dec 16 15:45:39 GMT 2023 , Edited by admin on Sat Dec 16 15:45:39 GMT 2023
PRIMARY
CAS
2249927-58-8
Created by admin on Sat Dec 16 15:45:39 GMT 2023 , Edited by admin on Sat Dec 16 15:45:39 GMT 2023
PRIMARY
From To
1_153 1_179
1_248 1_329
1_528 1_554
1_630 1_711
1_938 1_964
1_1005 1_1009
1_1280 1_1432
1_1127 1_1275
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_41
N 1_239
N 1_916
N 1_1224
Related Record Type Details
ACTIVE MOIETY
Blood coagulation factor replacements
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL