CIFOSTODINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H12N3O7P
Molecular Weight	305.1812
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CIFOSTODINE

Structure Search

SMILES

NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@H]3OP(O)(=O)O[C@@H]23

InChI

InChIKey=NMPZCCZXCOMSDQ-XVFCMESISA-N

InChI=1S/C9H12N3O7P/c10-5-1-2-12(9(14)11-5)8-7-6(4(3-13)17-8)18-20(15,16)19-7/h1-2,4,6-8,13H,3H2,(H,15,16)(H2,10,11,14)/t4-,6-,7-,8-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C9H12N3O7P
Molecular Weight	305.1812
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/25139571 | https://www.ncbi.nlm.nih.gov/pubmed/25817170 | https://www.ncbi.nlm.nih.gov/pubmed/15497691

Cifostodine is 2',3'-cyclic pyrimidine nucleotide formed during digestion of ribonucleic acid by ribonuclease. Cifostodine was recently identified in certain mammalian tissues such as the brain and kidney.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Identification of cytidine 2',3'-cyclic monophosphate and uridine 2',3'-cyclic monophosphate in Pseudomonas fluorescens pfo-1 culture.	2014-09-15	25139571

Patents

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:27:32 GMT 2025` Edited by `admin` on `Mon Mar 31 18:27:32 GMT 2025`
Record UNII	74B4VJV0WV
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

cifostodine [INN]

Preferred Name

English

CIFOSTODINE

Official Name

English

Classification Tree Code System Code

NCI_THESAURUS

C709

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C76915

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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EPA CompTox

DTXSID90212690

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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RXCUI

2477852

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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DAILYMED

74B4VJV0WV

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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ChEMBL

CHEMBL2104086

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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CAS

633-90-9

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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CHEBI

27652

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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MESH

C019310

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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PUBCHEM

68934

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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ECHA (EC/EINECS)

211-198-5

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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INN

5435

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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SMS_ID

100000081309

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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FDA UNII

74B4VJV0WV

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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EVMPD

SUB06259MIG

Created by admin on Mon Mar 31 18:27:32 GMT 2025 , Edited by admin on Mon Mar 31 18:27:32 GMT 2025

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Related Record Type Details


					74B4VJV0WV

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