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Details

Stereochemistry RACEMIC
Molecular Formula C15H21NO2.ClH
Molecular Weight 283.794
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EUCAINE HYDROCHLORIDE

SMILES

Cl.C[C@H]1C[C@H](CC(C)(C)N1)OC(=O)C2=CC=CC=C2

InChI

InChIKey=VGVCYHBQSIQXMO-STEACBGWSA-N
InChI=1S/C15H21NO2.ClH/c1-11-9-13(10-15(2,3)16-11)18-14(17)12-7-5-4-6-8-12;/h4-8,11,13,16H,9-10H2,1-3H3;1H/t11-,13+;/m0./s1

HIDE SMILES / InChI
Molecular Formula C15H21NO2
Molecular Weight 247.3327
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

1897
13
Doses

Doses

DosePopulationAdverse events​
8 % 1 times / day single, topical
Studied dose
Dose: 8 %, 1 times / day
Route: topical
Route: single
Dose: 8 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
unhealthy, 25 years
n = 1
Health Status: unhealthy
Condition: otitis media
Age Group: 25 years
Sex: M
Population Size: 1
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
Other AEs: Syncope, Irregular pulse...
Other AEs:
Syncope
Irregular pulse
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
8 % 1 times / day single, topical
Studied dose
Dose: 8 %, 1 times / day
Route: topical
Route: single
Dose: 8 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
unhealthy, 70 years
n = 1
Health Status: unhealthy
Condition: new growth in the right nostril
Age Group: 70 years
Sex: F
Population Size: 1
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
Other AEs: Faintness...
Other AEs:
Faintness
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
AEs

AEs

AESignificanceDosePopulation
Irregular pulse
8 % 1 times / day single, topical
Studied dose
Dose: 8 %, 1 times / day
Route: topical
Route: single
Dose: 8 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
unhealthy, 25 years
n = 1
Health Status: unhealthy
Condition: otitis media
Age Group: 25 years
Sex: M
Population Size: 1
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
Syncope
8 % 1 times / day single, topical
Studied dose
Dose: 8 %, 1 times / day
Route: topical
Route: single
Dose: 8 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
unhealthy, 25 years
n = 1
Health Status: unhealthy
Condition: otitis media
Age Group: 25 years
Sex: M
Population Size: 1
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
Faintness
8 % 1 times / day single, topical
Studied dose
Dose: 8 %, 1 times / day
Route: topical
Route: single
Dose: 8 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
unhealthy, 70 years
n = 1
Health Status: unhealthy
Condition: new growth in the right nostril
Age Group: 70 years
Sex: F
Population Size: 1
Sources:
https://pubmed.ncbi.nlm.nih.gov/20756737/
Sourcing

Sourcing

Vendor/AggregatorIDURL
1PlusChem LLC
1P01EXQ1
Alfa Chemistry
ACM555282
Compound Cloud
10373
Fluorochem
200380
Fluorochem
31074
MolPort
MolPort-000-164-391
MolPort
MolPort-006-111-817
NCI Plated 2007
49860
Oakwood
31074
ZINC
ZINC000000319774
http://zinc15.docking.org/substances/ZINC000000319774
eMolecules
107001980
eMolecules
27266280
PubMed

PubMed

TitleDatePubMed
Beta-eucaine bottle.
2009 Feb
Patents

Patents

20010004644
50
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:13:11 GMT 2023
Edited
by admin
on Fri Dec 15 15:13:11 GMT 2023
Record UNII
73NDV3S9Y7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EUCAINE HYDROCHLORIDE
Common Name English
BETAEUCAINE HYDROCHLORIDE
Common Name English
BETACAINE HYDROCHLORIDE
Common Name English
2,2,6-TRIMETHYLPIPERIDIN-4-YL BENZOATE HYDROCHLORIDE
Systematic Name English
4-PIPERIDINOL, 2,2,6-TRIMETHYL-, BENZOATE, HYDROCHLORIDE
Systematic Name English
EUCAINE HCL
Common Name English
.BETA.-EUCAINE HYDROCHLORIDE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C245
Created by admin on Fri Dec 15 15:13:11 GMT 2023 , Edited by admin on Fri Dec 15 15:13:11 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID30970843
Created by admin on Fri Dec 15 15:13:11 GMT 2023 , Edited by admin on Fri Dec 15 15:13:11 GMT 2023
PRIMARY
FDA UNII
73NDV3S9Y7
Created by admin on Fri Dec 15 15:13:11 GMT 2023 , Edited by admin on Fri Dec 15 15:13:11 GMT 2023
PRIMARY
CAS
555-28-2
Created by admin on Fri Dec 15 15:13:11 GMT 2023 , Edited by admin on Fri Dec 15 15:13:11 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110936
Created by admin on Fri Dec 15 15:13:11 GMT 2023 , Edited by admin on Fri Dec 15 15:13:11 GMT 2023
PRIMARY
PUBCHEM
20055420
Created by admin on Fri Dec 15 15:13:11 GMT 2023 , Edited by admin on Fri Dec 15 15:13:11 GMT 2023
PRIMARY
NCI_THESAURUS
C75094
Created by admin on Fri Dec 15 15:13:11 GMT 2023 , Edited by admin on Fri Dec 15 15:13:11 GMT 2023
PRIMARY
ECHA (EC/EINECS)
209-087-1
Created by admin on Fri Dec 15 15:13:11 GMT 2023 , Edited by admin on Fri Dec 15 15:13:11 GMT 2023
PRIMARY
Related Record Type Details
Structure of EUCAINE
PARENT -> SALT/SOLVATE
NIH
NCATS
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