EUCAINE HYDROCHLORIDE

US Previously Marketed

First marketed in 1897

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H21NO2.ClH
Molecular Weight	283.794
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.C[C@H]1C[C@H](CC(C)(C)N1)OC(=O)C2=CC=CC=C2

InChI

InChIKey=VGVCYHBQSIQXMO-STEACBGWSA-N

InChI=1S/C15H21NO2.ClH/c1-11-9-13(10-15(2,3)16-11)18-14(17)12-7-5-4-6-8-12;/h4-8,11,13,16H,9-10H2,1-3H3;1H/t11-,13+;/m0./s1

HIDE SMILES / InChI

Molecular Formula	C15H21NO2
Molecular Weight	247.3327
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Doses

Dose	Population	Adverse events
8 % 1 times / day single, topical Studied dose Dose: 8 %, 1 times / day Route: topical Route: single Dose: 8 %, 1 times / day Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/	unhealthy, 25 years Health Status: unhealthy Age Group: 25 years Sex: M Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/	Other AEs: Syncope, Irregular pulse... Other AEs: Syncope Irregular pulse Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/
8 % 1 times / day single, topical Studied dose Dose: 8 %, 1 times / day Route: topical Route: single Dose: 8 %, 1 times / day Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/	unhealthy, 70 years Health Status: unhealthy Age Group: 70 years Sex: F Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/	Other AEs: Faintness... Other AEs: Faintness Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/

AEs

AE	Dose	Population
Irregular pulse	8 % 1 times / day single, topical Studied dose Dose: 8 %, 1 times / day Route: topical Route: single Dose: 8 %, 1 times / day Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/	unhealthy, 25 years Health Status: unhealthy Age Group: 25 years Sex: M Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/
Syncope	8 % 1 times / day single, topical Studied dose Dose: 8 %, 1 times / day Route: topical Route: single Dose: 8 %, 1 times / day Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/	unhealthy, 25 years Health Status: unhealthy Age Group: 25 years Sex: M Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/
Faintness	8 % 1 times / day single, topical Studied dose Dose: 8 %, 1 times / day Route: topical Route: single Dose: 8 %, 1 times / day Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/	unhealthy, 70 years Health Status: unhealthy Age Group: 70 years Sex: F Sources: https://pubmed.ncbi.nlm.nih.gov/20756737/

Sourcing

Vendor/Aggregator	ID	URL
1PlusChem LLC	1P01EXQ1
Alfa Chemistry	ACM555282
Compound Cloud	10373
eMolecules	107001980
eMolecules	27266280
Fluorochem	200380
Fluorochem	31074
MolPort	MolPort-000-164-391
MolPort	MolPort-006-111-817
NCI Plated 2007	49860
Oakwood	31074
ZINC	ZINC000000319774	http://zinc15.docking.org/substances/ZINC000000319774

PubMed

Title	Date	PubMed
Beta-eucaine bottle.	2009-02	19164961

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:50:35 GMT 2025` Edited by `admin` on `Mon Mar 31 17:50:35 GMT 2025`
Record UNII	73NDV3S9Y7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BETACAINE HYDROCHLORIDE

Preferred Name

English

EUCAINE HYDROCHLORIDE

Common Name

English

BETAEUCAINE HYDROCHLORIDE

Common Name

English

2,2,6-TRIMETHYLPIPERIDIN-4-YL BENZOATE HYDROCHLORIDE

Systematic Name

English

4-PIPERIDINOL, 2,2,6-TRIMETHYL-, BENZOATE, HYDROCHLORIDE

Systematic Name

English

EUCAINE HCL

Common Name

English

.BETA.-EUCAINE HYDROCHLORIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C245