ARTEMETIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H20O8
Molecular Weight	388.368
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=C(C(=O)C(OC)=C(O2)C3=CC(OC)=C(OC)C=C3)C(O)=C1OC

InChI

InChIKey=RIGYMJVFEJNCKD-UHFFFAOYSA-N

InChI=1S/C20H20O8/c1-23-11-7-6-10(8-12(11)24-2)18-20(27-5)17(22)15-13(28-18)9-14(25-3)19(26-4)16(15)21/h6-9,21H,1-5H3

HIDE SMILES / InChI

Molecular Formula	C20H20O8
Molecular Weight	388.368
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Anti-inflammatory activity and sub-acute toxicity of artemetin.	1990 Feb	2356241
cDNA cloning and characterization of a 3'/5'-O-methyltransferase for partially methylated flavonols from Chrysosplenium americanum.	1996 Dec	9002616
In vitro cytotoxicity of flavonoids against MK2 and C6 tumour cells.	2001 Jun	11406849
New diterpenes and norditerpenes from the fruits of Vitex rotundifolia.	2002 Apr	11975496
Evaluation of the antiedematogenic activity of artemetin isolated from Cordia curassavica DC.	2002 Oct	12424497
Phenolic compounds and flavonoids as plant growth regulators from fruit and leaf of Vitex rotundifolia.	2004 Jul-Aug	15813370
G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.).	2004 May 10	15105046
Flavonoids from Vitex trifolia L. inhibit cell cycle progression at G2/M phase and induce apoptosis in mammalian cancer cells.	2005 Aug	16087636
Ethnoveterinary medicines used for horses in Trinidad and in British Columbia, Canada.	2006 Aug 7	16893454
[Studies on chemical constituents in herb from Artemisia rupestris].	2006 Nov	17260794
New antifungal flavonoid glycoside from Vitex negundo.	2007 Jan 1	17027268
[Studies on constitutes from Taraxacum mongolicum].	2007 May	17655148
Antiherpevirus activity of Artemisia arborescens essential oil and inhibition of lateral diffusion in Vero cells.	2007 Sep 26	17894898
[Studies on chemical constituents from herbs of Taraxacum mongolicum].	2008 May	18720865
One new triterpene ester from Nepeta suavis.	2009 Dec	20183267
Chemical composition and antibacterial activity of Cordia verbenacea extracts obtained by different methods.	2009 Dec	19683436
Antiproliferative effect of flavonoids and sesquiterpenoids from Achillea millefolium s.l. on cultured human tumour cell lines.	2009 May	19107850
A high-speed counter-current chromatography- HPLC-DAD method for preparative isolation and purification of two polymethoxylated flavones from Taraxacum mongolicum.	2009 May-Jun	19476701
Antiinflammatory and lipoxygenase inhibitory compounds from Vitex agnus-castus.	2009 Sep	19173281
[Preparative isolation and purification of the active components from Viticis Fructus by high-speed counter-current chromatography].	2010 Nov	21381420
Screening for in vitro phototoxic activity of methanol extracts of Croton campestris A., Ocimum gratissimum L. & Cordia verbenaceae DC.	2010 Nov	21150001
Hypotensive mechanism of the extracts and artemetin isolated from Achillea millefolium L. (Asteraceae) in rats.	2011 Jul 15	21420289
Antioxidant and hepatoprotective effects of ethanol extract of Vitex glabrata on carbon tetrachloride-induced liver damage in rats.	2012	22054305

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:50:47 GMT 2023` Edited by `admin` on `Fri Dec 15 17:50:47 GMT 2023`
Record UNII	73KMT7R64H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ARTEMETIN

Common Name

English

5-HYDROXY-3,3',4',6,7-PENTAMETHOXY-FLAVONE

Systematic Name

English

5-HYDROXY-3,3',4',6,7-PENTAMETHOXYFLAVONE

Systematic Name

English

Code System Code Type Description

FDA UNII

73KMT7R64H