ARTEMETIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H20O8
Molecular Weight	388.368
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=C(C(=O)C(OC)=C(O2)C3=CC(OC)=C(OC)C=C3)C(O)=C1OC

InChI

InChIKey=RIGYMJVFEJNCKD-UHFFFAOYSA-N

InChI=1S/C20H20O8/c1-23-11-7-6-10(8-12(11)24-2)18-20(27-5)17(22)15-13(28-18)9-14(25-3)19(26-4)16(15)21/h6-9,21H,1-5H3

HIDE SMILES / InChI

Molecular Formula	C20H20O8
Molecular Weight	388.368
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Antioxidant and hepatoprotective effects of ethanol extract of Vitex glabrata on carbon tetrachloride-induced liver damage in rats.	2012	22054305
Hypotensive mechanism of the extracts and artemetin isolated from Achillea millefolium L. (Asteraceae) in rats.	2011-07-15	21420289
[Preparative isolation and purification of the active components from Viticis Fructus by high-speed counter-current chromatography].	2010-11	21381420
Screening for in vitro phototoxic activity of methanol extracts of Croton campestris A., Ocimum gratissimum L. & Cordia verbenaceae DC.	2010-11	21150001
One new triterpene ester from Nepeta suavis.	2009-12	20183267
Chemical composition and antibacterial activity of Cordia verbenacea extracts obtained by different methods.	2009-12	19683436
Antiinflammatory and lipoxygenase inhibitory compounds from Vitex agnus-castus.	2009-09	19173281
A high-speed counter-current chromatography- HPLC-DAD method for preparative isolation and purification of two polymethoxylated flavones from Taraxacum mongolicum.	2009-05-30	19476701
Antiproliferative effect of flavonoids and sesquiterpenoids from Achillea millefolium s.l. on cultured human tumour cell lines.	2009-05	19107850
[Studies on chemical constituents from herbs of Taraxacum mongolicum].	2008-05	18720865
Antiherpevirus activity of Artemisia arborescens essential oil and inhibition of lateral diffusion in Vero cells.	2007-09-26	17894898
[Studies on constitutes from Taraxacum mongolicum].	2007-05	17655148
New antifungal flavonoid glycoside from Vitex negundo.	2007-01-01	17027268
[Studies on chemical constituents in herb from Artemisia rupestris].	2006-11	17260794
Ethnoveterinary medicines used for horses in Trinidad and in British Columbia, Canada.	2006-08-07	16893454
Flavonoids from Vitex trifolia L. inhibit cell cycle progression at G2/M phase and induce apoptosis in mammalian cancer cells.	2005-08	16087636
Phenolic compounds and flavonoids as plant growth regulators from fruit and leaf of Vitex rotundifolia.	2005-04-09	15813370
G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.).	2004-05-10	15105046
Evaluation of the antiedematogenic activity of artemetin isolated from Cordia curassavica DC.	2002-10	12424497
New diterpenes and norditerpenes from the fruits of Vitex rotundifolia.	2002-04	11975496
In vitro cytotoxicity of flavonoids against MK2 and C6 tumour cells.	2001-06	11406849
cDNA cloning and characterization of a 3'/5'-O-methyltransferase for partially methylated flavonols from Chrysosplenium americanum.	1996-12	9002616
Anti-inflammatory activity and sub-acute toxicity of artemetin.	1990-02	2356241

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:54:59 GMT 2025` Edited by `admin` on `Mon Mar 31 18:54:59 GMT 2025`
Record UNII	73KMT7R64H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

5-HYDROXY-3,3',4',6,7-PENTAMETHOXY-FLAVONE

Preferred Name

English

ARTEMETIN

Common Name

English

5-HYDROXY-3,3',4',6,7-PENTAMETHOXYFLAVONE

Systematic Name

English

Code System Code Type Description

FDA UNII

73KMT7R64H