Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C8H14N2O2 |
| Molecular Weight | 170.209 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC[C@@H](N1CCCC1=O)C(N)=O
InChI
InChIKey=HPHUVLMMVZITSG-ZCFIWIBFSA-N
InChI=1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m1/s1
| Molecular Formula | C8H14N2O2 |
| Molecular Weight | 170.209 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| New migraine preventive options: an update with pathophysiological considerations. | 2003-03-04 |
|
| Electrophysiological, neurochemical and regional effects of levetiracetam in the rat pilocarpine model of temporal lobe epilepsy. | 2003-03 |
|
| Effects of lamotrigine and levetiracetam on seizure development in a rat amygdala kindling model. | 2003-02 |
|
| Evidence for sustained efficacy of levetiracetam as add-on epilepsy therapy. | 2003-02 |
|
| Effects of antiepileptic comedication on levetiracetam pharmacokinetics: a pooled analysis of data from randomized adjunctive therapy trials. | 2003-02 |
|
| Levetiracetam efficacy in refractory partial-onset seizures, especially after failed epilepsy surgery. | 2003-02 |
|
| Levetiracetam, a new antiepileptic agent: lack of in vitro and in vivo pharmacokinetic interaction with valproic acid. | 2003-02 |
|
| Correlation of levetiracetam concentrations between serum and saliva. | 2003-02 |
|
| Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation. | 2003-01-02 |
|
| Successful treatment of pharmacoresistent continuous spike wave activity during slow sleep with levetiracetam. | 2003-01 |
|
| A paradoxical effect of levetiracetam may be seen in both children and adults with refractory epilepsy. | 2003-01 |
|
| Relevance of new and newly rediscovered anticonvulsants for atypical forms of bipolar disorder. | 2002-12 |
|
| Effect of levetiracetam on rapid motor learning in humans. | 2002-12 |
|
| Levetiracetam may be more effective for late-onset partial epilepsy. | 2002-12 |
|
| Effect of levetiracetam on epileptiform discharges in human neocortical slices. | 2002-12 |
|
| New antiepileptic drug therapies. | 2002-11 |
|
| Improvement of a patient with stuttering on levetiracetam. | 2002-10-22 |
|
| Amelioration of spinal myoclonus with levetiracetam. | 2002-10 |
|
| Antiepileptic drug use during the first 12 months of vagus nerve stimulation therapy: a registry study. | 2002-09-24 |
|
| [Effectiveness and tolerability of the new antiepileptic drugs: the position of levetiracetam]. | 2002-09-18 |
|
| Use of anticonvulsants for treatment of neuropathic pain. | 2002-09-10 |
|
| [Characteristics and indications of levetiracetam]. | 2002-09 |
|
| Progress report on new antiepileptic drugs: a summary of the Sixth Eilat Conference (EILAT VI). | 2002-09 |
|
| The effects of levetiracetam on objective and subjective sleep parameters in healthy volunteers and patients with partial epilepsy. | 2002-09 |
|
| Levetiracetam in autistic children: an open-label study. | 2002-08 |
|
| Aggravation of partial seizures by antiepileptic drugs: is there evidence from clinical trials? | 2002-07-09 |
|
| Levetiracetam does not alter the pharmacokinetics of an oral contraceptive in healthy women. | 2002-07 |
|
| The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents. | 2002-07 |
|
| [Levetiracetam: an anti-epileptic drug with interesting pharmacokinetic properties]. | 2002-06-29 |
|
| Levetiracetam in refractory pediatric epilepsy. | 2002-06 |
|
| Gateways to Clinical Trials. June 2002. | 2002-06 |
|
| [Levetiracetam: a molecule with a novel mechanism of action in the pharmaceutical treatment of epilepsy]. | 2002-05-20 |
|
| Levetiracetam in the treatment of paroxysmal kinesiogenic choreoathetosis. | 2002-05 |
|
| Efficacy and safety of levetiracetam in children with partial seizures: an open-label trial. | 2002-05 |
|
| The 'number needed to treat' with levetiracetam (LEV): comparison with the other new antiepileptic drugs (AEDs). | 2002-04 |
|
| Levetiracetam--a new drug for epilepsy. | 2002-04 |
|
| Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy. | 2002-04 |
|
| The new antiepileptic drug levetiracetam normalises chlordiazepoxide withdrawal-induced anxiety in mice. | 2002-03-29 |
|
| Some common issues in the use of antiepileptic drugs. | 2002-03 |
|
| Suppression of cortical myoclonus by levetiracetam. | 2002-03 |
|
| A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsy. | 2002-03 |
|
| Carbamazepine toxicity during combination therapy with levetiracetam: a pharmacodynamic interaction. | 2002-02 |
|
| Pediatric partial and generalized seizures. | 2002-01 |
|
| Using the new antiepilepsy drugs in children. | 2002-01 |
|
| Rat models of genetic absence epilepsy: what do EEG spike-wave discharges tell us about drug effects? | 2002 |
|
| A case of levetiracetam (Keppra) poisoning with clinical and toxicokinetic data. | 2002 |
|
| Pharmacokinetics of mood stabilizers and new anticonvulsants. | 2002 |
|
| New and emerging prophylactic agents for migraine. | 2002 |
|
| Treatment of epilepsy in women of reproductive age: pharmacokinetic considerations. | 2002 |
|
| Interactions between antiepileptic drugs and hormonal contraception. | 2002 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:39:44 GMT 2025
by
admin
on
Mon Mar 31 20:39:44 GMT 2025
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| Record UNII |
73HC18Y1LW
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| Record Status |
Validated (UNII)
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| Record Version |
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103765-01-1
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DTXSID10146044
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73HC18Y1LW
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441341
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