ZIRAM

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C3H6NS2.Zn
Molecular Weight	305.842
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Zn++].CN(C)C([S-])=S.CN(C)C([S-])=S

InChI

InChIKey=DUBNHZYBDBBJHD-UHFFFAOYSA-L

InChI=1S/2C3H7NS2.Zn/c2*1-4(2)3(5)6;/h2*1-2H3,(H,5,6);/q;;+2/p-2

HIDE SMILES / InChI

Molecular Formula	C3H7NS2
Molecular Weight	121.224
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Zn
Molecular Weight	65.409
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Decreased fertility, increased dominant lethals, skeletal malformations induced in the mouse by Ziram fungicide.	1983 Jul-Sep	6230523
The antifertility and antiadrenergic actions of thiocarbamate fungicides in laying hens.	1984 Feb	6420938
90-day oral toxicity of ziram: a thyrostatic and hepatotoxic study.	1990	15092255
Clastogenic effects of the dithiocarbamate fungicides thiram and ziram in Chinese hamster cell lines cultured in vitro.	1994	7940406
Thyroid peroxidase as toxicity target for dithiocarbamates.	1997	9248629
Determination of the sensitising activity of the rubber contact sensitisers TMTD, ZDMC, MBT and DEA in a modified local lymph node assay and the effect of sodium dodecyl sulfate pretreatment on local lymph node responses.	2002 Jul 1	12062936
Retinal degeneration and other eye disorders in wives of farmer pesticide applicators enrolled in the agricultural health study.	2005 Jun 1	15901622
Muscular contractions in the zebrafish embryo are necessary to reveal thiuram-induced notochord distortions.	2006 Apr 1	16051294
Molecular mechanisms underlying mancozeb-induced inhibition of TNF-alpha production.	2006 Apr 15	16112155
Effects of possible endocrine disrupting chemicals on bacterial component-induced activation of NF-kappaB.	2006 Oct	17015962
Induction of tibial dyschondroplasia by carbamate and thiocarbamate pesticides.	2007 Jun	17626489
Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome.	2008 Dec 12	18818210
Effects of possible endocrine disruptors on MyD88-independent TLR4 signaling.	2008 Mar	18177342
Effects of ziram on tumor-cell-binding capacity, cell-surface marker expression, and ATP levels of human natural killer cells.	2009 Oct	18670896
Ziram induces apoptosis and necrosis in human immune cells.	2011 Apr	20842346
Parkinson's disease risk from ambient exposure to pesticides.	2011 Jul	21505849
Ziram activates mitogen-activated protein kinases and decreases cytolytic protein levels in human natural killer cells.	2011 Oct	21859362
Mechanism of ziram-induced apoptosis in human T lymphocytes.	2012 Apr	22159898
Effect of ziram on natural killer, lymphokine-activated killer, and cytotoxic T lymphocyte activity.	2012 Mar	22038140
Ziram and sodium N,N-dimethyldithiocarbamate inhibit ubiquitin activation through intracellular metal transport and increased oxidative stress in HEK293 cells.	2015 Apr 20	25714994
Zinc- and oxidative property-dependent degradation of pro-caspase-1 and NLRP3 by ziram in mouse macrophages.	2015 Jun 15	25929180

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 03:01:49 GMT 2023` Edited by `admin` on `Sat Dec 16 03:01:49 GMT 2023`
Record UNII	73D8UA974J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ZIRAM

Common Name

English

ZINC BIS(DIMETHYLCARBAMODITHIOATE)

Systematic Name

English

NSC-737

Code

English

ZIRAM [ISO]

Common Name

English

THIONIC

Brand Name

English

MEZENE

Brand Name

English

TRISCABOL

Brand Name

English

DIMETHYLDITHIOCARBAMIC ACID ZINC SALT

Common Name

English

(T-4)-BIS(N,N-DIMETHYLCARBAMODITHIOATO-.KAPPA.S,.KAPPA.S')ZINC

Common Name

English

CARBAMODITHIOIC ACID, N,N-DIMETHYL-, ZINC SALT (2:1)

Common Name

English

ZIRAM [MI]

Common Name

English

POMARSOL Z

Brand Name

English

ZINC DIMETHYLDITHIOCARBAMATE

Systematic Name

English

ZIRAM [HSDB]

Common Name

English

METHYL CYMATE

Systematic Name

English

ZIRAM (ZINC DIMETHYLDITHIOCARBAMATE)

Common Name

English

ZIRAM [IARC]

Common Name

English

CRITTAM

Brand Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

34805