ZIRAM

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C3H6NS2.Zn
Molecular Weight	305.842
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Zn++].CN(C)C([S-])=S.CN(C)C([S-])=S

InChI

InChIKey=DUBNHZYBDBBJHD-UHFFFAOYSA-L

InChI=1S/2C3H7NS2.Zn/c2*1-4(2)3(5)6;/h2*1-2H3,(H,5,6);/q;;+2/p-2

HIDE SMILES / InChI

Molecular Formula	Zn
Molecular Weight	65.409
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C3H7NS2
Molecular Weight	121.224
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Zinc- and oxidative property-dependent degradation of pro-caspase-1 and NLRP3 by ziram in mouse macrophages.	2015-06-15	25929180
Ziram and sodium N,N-dimethyldithiocarbamate inhibit ubiquitin activation through intracellular metal transport and increased oxidative stress in HEK293 cells.	2015-04-20	25714994
Mechanism of ziram-induced apoptosis in human T lymphocytes.	2012-04	22159898
Effect of ziram on natural killer, lymphokine-activated killer, and cytotoxic T lymphocyte activity.	2012-03	22038140
Ziram activates mitogen-activated protein kinases and decreases cytolytic protein levels in human natural killer cells.	2011-10	21859362
Parkinson's disease risk from ambient exposure to pesticides.	2011-07	21505849
Ziram induces apoptosis and necrosis in human immune cells.	2011-04	20842346
Effects of ziram on tumor-cell-binding capacity, cell-surface marker expression, and ATP levels of human natural killer cells.	2009-10	18670896
Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome.	2008-12-12	18818210
Effects of possible endocrine disruptors on MyD88-independent TLR4 signaling.	2008-03	18177342
Induction of tibial dyschondroplasia by carbamate and thiocarbamate pesticides.	2007-06	17626489
Effects of possible endocrine disrupting chemicals on bacterial component-induced activation of NF-kappaB.	2006-10	17015962
Molecular mechanisms underlying mancozeb-induced inhibition of TNF-alpha production.	2006-04-15	16112155
Muscular contractions in the zebrafish embryo are necessary to reveal thiuram-induced notochord distortions.	2006-04-01	16051294
Retinal degeneration and other eye disorders in wives of farmer pesticide applicators enrolled in the agricultural health study.	2005-06-01	15901622
Determination of the sensitising activity of the rubber contact sensitisers TMTD, ZDMC, MBT and DEA in a modified local lymph node assay and the effect of sodium dodecyl sulfate pretreatment on local lymph node responses.	2002-07-01	12062936
Thyroid peroxidase as toxicity target for dithiocarbamates.	1997	9248629
Clastogenic effects of the dithiocarbamate fungicides thiram and ziram in Chinese hamster cell lines cultured in vitro.	1994	7940406
90-day oral toxicity of ziram: a thyrostatic and hepatotoxic study.	1990	15092255
The antifertility and antiadrenergic actions of thiocarbamate fungicides in laying hens.	1984-02	6420938
Decreased fertility, increased dominant lethals, skeletal malformations induced in the mouse by Ziram fungicide.	1983-07-01	6230523

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:16:20 GMT 2025` Edited by `admin` on `Mon Mar 31 21:16:20 GMT 2025`
Record UNII	73D8UA974J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ZIRAM

Common Name

English

CRITTAM

Preferred Name

English

ZINC BIS(DIMETHYLCARBAMODITHIOATE)

Systematic Name

English

NSC-737

Code

English

ZIRAM [ISO]

Common Name

English

THIONIC

Brand Name

English

MEZENE

Brand Name

English

TRISCABOL

Brand Name

English

DIMETHYLDITHIOCARBAMIC ACID ZINC SALT

Common Name

English

(T-4)-BIS(N,N-DIMETHYLCARBAMODITHIOATO-.KAPPA.S,.KAPPA.S')ZINC

Common Name

English

CARBAMODITHIOIC ACID, N,N-DIMETHYL-, ZINC SALT (2:1)

Common Name

English

ZIRAM [MI]

Common Name

English

POMARSOL Z

Brand Name

English

ZINC DIMETHYLDITHIOCARBAMATE

Systematic Name

English

ZIRAM [HSDB]

Common Name

English

METHYL CYMATE

Systematic Name

English

ZIRAM (ZINC DIMETHYLDITHIOCARBAMATE)

Common Name

English

ZIRAM [IARC]

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

34805