DRISAPERSEN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 05:49:13 GMT 2023` Edited by `admin` on `Sat Dec 16 05:49:13 GMT 2023`
Nucleic Acid Subtype
Sequence Type	OLIGONUCLEOTIDE
Record UNII	73D586DAMF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DRISAPERSEN

Official Name

English

GSK2402968A

Code

English

PRO051

Code

English

GSK-2402968

Code

English

H51AON23

Code

English

Drisapersen [WHO-DD]

Common Name

English

DRISAPERSEN [USAN]

Common Name

English

GSK 2402968A

Common Name

English

drisapersen [INN]

Common Name

English

GSK-2402968A

Code

English

GSK2402968

Code

English

PRO-051

Code

English

RNA, (P-THIO)(UM-CM-AM-AM-GM-GM-AM-AM-GM-AM-UM-GM-GM-CM-AM-UM-UM-UM-CM-UM)

Common Name

English

Classification Tree Code System Code

WHO-ATC

M09AX04

Created by admin on Sat Dec 16 05:49:13 GMT 2023 , Edited by admin on Sat Dec 16 05:49:13 GMT 2023

Code System Code Type Description

EVMPD

SUB129424

Created by admin on Sat Dec 16 05:49:13 GMT 2023 , Edited by admin on Sat Dec 16 05:49:13 GMT 2023

PRIMARY

NCI_THESAURUS

C166984

Created by admin on Sat Dec 16 05:49:13 GMT 2023 , Edited by admin on Sat Dec 16 05:49:13 GMT 2023

PRIMARY

PUBCHEM

121494119

Created by admin on Sat Dec 16 05:49:13 GMT 2023 , Edited by admin on Sat Dec 16 05:49:13 GMT 2023

PRIMARY

WIKIPEDIA

Drisapersen

Created by admin on Sat Dec 16 05:49:13 GMT 2023 , Edited by admin on Sat Dec 16 05:49:13 GMT 2023

PRIMARY

FDA UNII

73D586DAMF

Created by admin on Sat Dec 16 05:49:13 GMT 2023 , Edited by admin on Sat Dec 16 05:49:13 GMT 2023

PRIMARY

USAN

YY-02

Created by admin on Sat Dec 16 05:49:13 GMT 2023 , Edited by admin on Sat Dec 16 05:49:13 GMT 2023

PRIMARY

CAS

1251830-50-8

Created by admin on Sat Dec 16 05:49:13 GMT 2023 , Edited by admin on Sat Dec 16 05:49:13 GMT 2023

PRIMARY

DRUG BANK

DB13688

Created by admin on Sat Dec 16 05:49:13 GMT 2023 , Edited by admin on Sat Dec 16 05:49:13 GMT 2023

PRIMARY

INN

9518

Created by admin on Sat Dec 16 05:49:13 GMT 2023 , Edited by admin on Sat Dec 16 05:49:13 GMT 2023

PRIMARY

ChEMBL

CHEMBL2108735

Created by admin on Sat Dec 16 05:49:13 GMT 2023 , Edited by admin on Sat Dec 16 05:49:13 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methyl-Ribose	1_1-1_20	20 / 20

Linkage	Site Range	Site Count
Phosporothioate	1_2-1_20	19 / 19

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TARGET -> INDUCER

Comments:

Completed Phase III trials and did not meet its primary endpoint. Alters the splicing of the dystrophin RNA transcript, eliminating exon 51 from the mature dystrophin mRNA.


					SDA7197G7Q

DRISAPERSEN SODIUM

SALT/SOLVATE -> PARENT

Related Record Type Details


					73D586DAMF

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL