Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Wed Apr 02 03:25:12 GMT 2025
by
admin
on
Wed Apr 02 03:25:12 GMT 2025
|
| Protein Sub Type | |
| Sequence Type | COMPLETE |
| Record UNII |
73C27N6Z7U
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Preferred Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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73C27N6Z7U
Created by
admin on Wed Apr 02 03:25:12 GMT 2025 , Edited by admin on Wed Apr 02 03:25:12 GMT 2025
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PRIMARY | |||
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9028-31-3
Created by
admin on Wed Apr 02 03:25:12 GMT 2025 , Edited by admin on Wed Apr 02 03:25:12 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
Reduces toxic galactitol levels and prevents disease complications in GALT deficiency. Brain penetrant.
IC50
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INHIBITOR -> TARGET |
https://en.wikipedia.org/wiki/Tolrestat
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INHIBITOR -> TARGET |
Discontinued : Diabetic complications
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
https://en.wikipedia.org/wiki/Crucibulum#Bioactive_compounds
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INHIBITOR -> TARGET |
Discontinued : Diabetic retinopathy
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
https://en.wikipedia.org/wiki/Sorbinil
Discontinued : Diabetes mellitus
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INHIBITOR -> TARGET |
Inactive Indications on highest development phases;
Discontinued : Diabetic cardiomyopathy; Diabetic nephropathies; Diabetic neuropathies
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
https://en.wikipedia.org/wiki/Zenarestat
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Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| AMINO ACID SUBSTITUTION | [1_1] |
Amount:
|
N-ACETYLALANINE | 26C4VY6Z0M | ||
| AMINO ACID SUBSTITUTION | [1_2] | SERINE | DEXFOSFOSERINE | VI4F0K069V | ||
| AMINO ACID SUBSTITUTION | [1_94] [1_221] [1_262] | LYSINE | N6-ACETYLLYSINE | 470AD5VY1X |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
|
||||
| Molecular Formula | CHEMICAL |
|