ECOMUSTINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H18ClN3O6
Molecular Weight	311.719
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CO[C@@H]1C[C@@H](NC(=O)N(CCCl)N=O)[C@H](O)[C@@H](CO)O1

InChI

InChIKey=YQYBWJPESSJLTK-HXFLIBJXSA-N

InChI=1S/C10H18ClN3O6/c1-19-8-4-6(9(16)7(5-15)20-8)12-10(17)14(13-18)3-2-11/h6-9,15-16H,2-5H2,1H3,(H,12,17)/t6-,7-,8+,9+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C10H18ClN3O6
Molecular Weight	311.719
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://adisinsight.springer.com/drugs/800000843 | https://www.ncbi.nlm.nih.gov/pubmed/3218975 | https://www.ncbi.nlm.nih.gov/pubmed/2103843 | https://www.ncbi.nlm.nih.gov/pubmed/2598412

Ecomustine, or CY233 (NSC-609224), is a water-soluble nitrosoureido derivative of deoxysugar exerting antineoplastic activity. It acts as an alkylating agent. It demonstrated effectivity in the treatment of tumors in animal models.

Originator

Approval Year

Sample Use Guides

In Vivo Use Guide

mice: 10-20 mg/kg

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:29:11 GMT 2023` Edited by `admin` on `Fri Dec 15 15:29:11 GMT 2023`
Record UNII	7369R4J7S2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ECOMUSTINE

Official Name

English

ecomustine [INN]

Common Name

English

NSC-609224

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C699