U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Thu Jul 06 23:26:50 UTC 2023
Edited
by admin
on Thu Jul 06 23:26:50 UTC 2023
Nucleic Acid Subtype
Record UNII
72JR7XDV94
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RILTOZINAMERAN
INN  
Official Name English
riltozinameran [INN]
Common Name English
Riltozinameran [WHO-DD]
Common Name English
BNT162B2_B.1.1.529
Code English
RNA (RECOMBINANT 5'-(1,2-((3'-O-METHYL)M7G-(5'->5')-PPP-AM))-CAPPED ALL URIDINE->N1-METHYLPSEUDOURIDINE-SUBSTITUTED SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN SECRETORY SIGNAL PEPTIDE PLUS CODON-OPTIMIZED SPIKE GLYCOPROTEIN B.1.1.
Common Name English
MESSENGER RNA (MRNA), 5'-CAPPED, ENCODING A FULL-LENGTH, CODON-OPTIMISED PRE-FUSION STABILISED CONFORMATION VARIANT (K983P AND V984P) OF THE SARS-COV-2 (SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; OMICRON VARIANT AND B.1.1.529 AND HCOV-19/BOTSWANA/R
Common Name English
Code System Code Type Description
FDA UNII
72JR7XDV94
Created by admin on Thu Jul 06 23:26:50 UTC 2023 , Edited by admin on Thu Jul 06 23:26:50 UTC 2023
PRIMARY
SMS_ID
300000042045
Created by admin on Thu Jul 06 23:26:50 UTC 2023 , Edited by admin on Thu Jul 06 23:26:50 UTC 2023
PRIMARY
INN
12510
Created by admin on Thu Jul 06 23:26:50 UTC 2023 , Edited by admin on Thu Jul 06 23:26:50 UTC 2023
PRIMARY
NCI_THESAURUS
C188525
Created by admin on Thu Jul 06 23:26:50 UTC 2023 , Edited by admin on Thu Jul 06 23:26:50 UTC 2023
PRIMARY
CAS
2749948-25-0
Created by admin on Thu Jul 06 23:26:50 UTC 2023 , Edited by admin on Thu Jul 06 23:26:50 UTC 2023
PRIMARY
Sugar Site Range Site Count
2'-O-Methyl-Ribose 1_1 1 / 4274
D-Ribose (RNA) 1_2-1_4274 4273 / 4274
Linkage Site Range Site Count
Phosphate 1_2-1_4274 4273 / 4273
Related Record Type Details
TARGET ORGANISM->VACCINE ANTIGEN
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
NUCLEOSIDE_SUBSTITUTION RESIDUE_SPECIFIC U N1-METHYLPSEUDOURIDINE 09RAD4M6WF
NUCLEOTIDE SUBSTITUTION [1_1] SITE_SPECIFIC m2-7,3’-OGppp(m1-2’-O)Ap mRNA CAP VNP8CZY34V