Talorasib

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C32H34ClFN6O3
Molecular Weight	605.102
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1CCC[C@H]1COC2=NC(N3CCN([C@@H](CC#N)C3)C(=O)C(F)=C)=C4CO[C@@H](CC4=N2)C5=C6C(Cl)=CC=CC6=CC=C5

InChI

InChIKey=DOUDKPJUSUTSCJ-LXWOLXCRSA-N

InChI=1S/C32H34ClFN6O3/c1-20(34)31(41)40-15-14-39(17-22(40)11-12-35)30-25-19-42-28(24-9-3-6-21-7-4-10-26(33)29(21)24)16-27(25)36-32(37-30)43-18-23-8-5-13-38(23)2/h3-4,6-7,9-10,22-23,28H,1,5,8,11,13-19H2,2H3/t22-,23-,28-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C32H34ClFN6O3
Molecular Weight	605.102
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 11:07:42 GMT 2025` Edited by `admin` on `Wed Apr 02 11:07:42 GMT 2025`
Record UNII	727W6T7DPK
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

2-Piperazineacetonitrile, 4-[(7S)-7-(8-chloro-1-naphthalenyl)-7,8-dihydro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-5H-pyrano[4,3-d]pyrimidin-4-yl]-1-(2-fluoro-1-oxo-2-propen-1-yl)-, (2S)-

Preferred Name

English

Talorasib

Official Name

English

talorasib [INN]

Common Name

English

(2S)-4-[(7S)-7-(8-Chloro-1-naphthalenyl)-7,8-dihydro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-5H-pyrano[4,3-d]pyrimidin-4-yl]-1-(2-fluoro-1-oxo-2-propen-1-yl)-2-piperazineacetonitrile

Systematic Name

English

[(2S)-4-[(7S)-7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile

Systematic Name

English

Code System Code Type Description

CAS

2620692-19-3