U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C8H10N2O
Molecular Weight 150.1778
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of P-NITROSO-N,N-DIMETHYLANILINE

SMILES

CN(C)C1=CC=C(C=C1)N=O

InChI

InChIKey=CMEWLCATCRTSGF-UHFFFAOYSA-N
InChI=1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3

HIDE SMILES / InChI

Molecular Formula C8H10N2O
Molecular Weight 150.1778
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
New tool to evaluate a comprehensive antioxidant activity in food extracts: bleaching of 4-nitroso-N,N-dimethylaniline catalyzed by soybean lipoxygenase-1.
2009-10-28
Alcohol dehydrogenase isoenzymes and aldehyde dehydrogenase activity in the sera of patients with esophageal cancer.
2009-06
Photodynamic efficacy of chlorin p6: a pH dependent study in aqueous and lipid environment.
2008-10-16
Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) activity in the sera of patients with pancreatic cancer.
2008-08
Photoprotection by porcine eumelanin against singlet oxygen production.
2008-04-22
Study on superoxide and hydroxyl radicals generated in indirect electrochemical oxidation by chemiluminescence and UV-Visible spectra.
2008
Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) activity in the sera of patients with liver cancer.
2008
Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) activity in the sera of patients with colorectal cancer.
2007-12
UV-Vis spectrophotometrical and analytical methodology for the determination of singlet oxygen in new antibacterials drugs.
2007-11-11
Alcohol dehydrogenase (ADH) isoenzyme activity in the sera of patients with Helicobacter pylori infection.
2007-06
Investigation of the effects of the local environment on the surface-enhanced Raman spectra of striped gold/silver nanorod arrays.
2007-04-10
The activity of class I, III, and IV of alcohol dehydrogenase isoenzymes and aldehyde dehydrogenase in gastric cancer.
2007-02
Uptake of N-nitrosodimethylamine (NDMA) from water by phreatophytes in the absence and presence of perchlorate as a co-contaminant.
2006-12-01
Modeling the formation of N-nitrosodimethylamine (NDMA) from the reaction of natural organic matter (NOM) with monochloramine.
2006-12-01
D-cycloserine facilitates extinction but does not eliminate renewal of the conditioned emotional response.
2006-10
The activity of class I, II, III and IV alcohol dehydrogenase isoenzymes and aldehyde dehydrogenase in breast cancer.
2006-06
The fate of wastewater-derived NDMA precursors in the aquatic environment.
2006-03
Synthesis, structure and anticancer activity of novel 2,4-diamino-1,3,5-triazine derivatives.
2006-02
Influence of the physiologically widespread substances on the oxidative activity of copper(II) complexes with sinefungin, a nucleoside antibiotic.
2006-02
Prostaglandin EP1 receptor contributes to excitotoxicity and focal ischemic brain damage.
2006-01
Optimization of the aerobic biological treatment of thermophilically treated refractory wastewater.
2005-10-17
A novel nicotinoprotein aldehyde dehydrogenase involved in polyethylene glycol degradation.
2005-09
Evidence for cytochrome P450 2E1 catalytic activity and expression in rat blood lymphocytes.
2005-07-22
Influence of the order of reagent addition on NDMA formation during chloramination.
2005-05-15
Degradation of N-nitrosodimethylamine (NDMA) in landscape soils.
2005-01-14
Intra- and intercellular variations in the repair efficiency of O6-methylguanine, and their contribution to kinetic complexity.
2004-12-21
Hydrophilic antimutagens in fermented defatted soybeans with Neurospora intermedia (D-oncom).
2004-12
The activity of class I, II, III, and IV alcohol dehydrogenase isoenzymes and aldehyde dehydrogenase in colorectal cancer.
2004-06
Prooxidant and antioxidant action of 4-(4-phenoxybenzoyl)benzoic acid derivatives.
2004-04-05
An endogenous metabolite of dopamine, 3,4-dihydroxyphenylethanol, acts as a unique cytoprotective agent against oxidative stress-induced injury.
2004-03-01
Non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) amplifies ionotropic glutamate receptor signaling in embryonic cerebellar granule neurons by a mechanism involving ryanodine receptors.
2004-01
P-nitrosodimethylaniline (RNO)-based evaluation of enhanced oxidative potential during electrochemical treatment of high-salinity wastewater.
2004
Nitrenium ions. Reactions of N,N-dimethyl-p-benzoyloxyanilineiminium chloride with indoles and indolizines. X-ray structure of unexpected [2-chloro-4-(4-dimethylaminophenyl-ONN-azoxy)phenylldimethylamine (azoxy derivative).
2003-11-07
Development of a high performance electrochemical wastewater treatment system.
2003-10-01
A N-Nitrosodimethylamine (NDMA) precursor analysis for chlorination of water and wastewater.
2003-09
3-alkyl- and 3-aryl-(7-oxo-7H-furo[3, 2-g]chromen-5-yl)alkanoic acids as inhibitors of leukotriene B4 biosynthesis.
2003-08
Enhancing effect of melatonin on chemiluminescence accompanying decomposition of hydrogen peroxide in the presence of copper.
2003-06-15
Solution chemistry of copper(II)-gentamicin complexes: relevance to metal-related aminoglycoside toxicity.
2003-03-10
Photochemical properties of kynurenine pathway metabolites and indoleamines.
2003
Dietary exposure and urinary excretion of total N-nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high- and low-risk areas for esophageal cancer in southern China.
2002-11-20
Spin trapping study of reactive oxygen species formation during bopindolol peroxidation.
2002-10-15
A sensitive, colorimetric, microtitre assay for alcohol dehydrogenase in standard endoscopic gastric biopsies.
2002-08
3-Alkyl- and 3-aryl-7H-furo[3,2-g]-1-benzopyran-7-ones: synthesis, photoreactivity, and fluorescence properties.
2002-05
Bioorganic mechanisms of the formation of free radicals catalyzed by glucose oxidase.
2002-04
DNA adducts and liver DNA replication in rats during chronic exposure to N-nitrosodimethylamine (NDMA) and their relationships to the dose-dependence of NDMA hepatocarcinogenesis.
2002-03-20
Formation of N-nitrosodimethylamine (NDMA) from dimethylamine during chlorination.
2002-02-15
NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2)receptors-implications for models of schizophrenia.
2002
A kinetic model of N-nitrosodimethylamine (NDMA) formation during water chlorination/chloramination.
2002
Formation of singlet oxygen during farmorubicin oxidation.
2001-09
Rapid kinetic evidence for adduct formation between the substrate analog p-nitroso-N,N-dimethylaniline and reduced nicotinamide-adenine dinucleotide during enzymic reduction.
1971-11-23
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:40:22 GMT 2025
Edited
by admin
on Mon Mar 31 18:40:22 GMT 2025
Record UNII
726V2ETM9E
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ACCELERINE
Preferred Name English
P-NITROSO-N,N-DIMETHYLANILINE
MI  
Common Name English
DIMETHYL-P-NITROSOANILINE, N,N-
Common Name English
NCI-C01821
Code English
NSC-2775
Code English
N,N-DIMETHYL-4-NITROSOANILINE
Systematic Name English
N,N-DIMETHYL-P-NITROSOANILINE [HSDB]
Common Name English
N,N-DIMETHYL-4-NITROSOBENZENAMINE
Systematic Name English
P-NITROSO-N,N-DIMETHYLANILINE [MI]
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID7025138
Created by admin on Mon Mar 31 18:40:22 GMT 2025 , Edited by admin on Mon Mar 31 18:40:22 GMT 2025
PRIMARY
MERCK INDEX
m7995
Created by admin on Mon Mar 31 18:40:22 GMT 2025 , Edited by admin on Mon Mar 31 18:40:22 GMT 2025
PRIMARY Merck Index
HSDB
1320
Created by admin on Mon Mar 31 18:40:22 GMT 2025 , Edited by admin on Mon Mar 31 18:40:22 GMT 2025
PRIMARY
ECHA (EC/EINECS)
205-343-1
Created by admin on Mon Mar 31 18:40:22 GMT 2025 , Edited by admin on Mon Mar 31 18:40:22 GMT 2025
PRIMARY
FDA UNII
726V2ETM9E
Created by admin on Mon Mar 31 18:40:22 GMT 2025 , Edited by admin on Mon Mar 31 18:40:22 GMT 2025
PRIMARY
NSC
2775
Created by admin on Mon Mar 31 18:40:22 GMT 2025 , Edited by admin on Mon Mar 31 18:40:22 GMT 2025
PRIMARY
PUBCHEM
8749
Created by admin on Mon Mar 31 18:40:22 GMT 2025 , Edited by admin on Mon Mar 31 18:40:22 GMT 2025
PRIMARY
CHEBI
59990
Created by admin on Mon Mar 31 18:40:22 GMT 2025 , Edited by admin on Mon Mar 31 18:40:22 GMT 2025
PRIMARY
CAS
138-89-6
Created by admin on Mon Mar 31 18:40:22 GMT 2025 , Edited by admin on Mon Mar 31 18:40:22 GMT 2025
PRIMARY