MONOPHOSPHOTHIAMINE INNER SALT

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H17N4O4PS
Molecular Weight	344.327
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MONOPHOSPHOTHIAMINE INNER SALT

Structure Search

SMILES

CC1=C(CCOP(O)([O-])=O)SC=[N+]1CC2=C(N)N=C(C)N=C2

InChI

InChIKey=HZSAJDVWZRBGIF-UHFFFAOYSA-N

InChI=1S/C12H17N4O4PS/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19)

HIDE SMILES / InChI

Molecular Formula	C12H17N4O4PS
Molecular Weight	344.327
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5151224 | https://www.ncbi.nlm.nih.gov/pubmed/5734623 | https://www.ncbi.nlm.nih.gov/pubmed/676062 | https://www.rlsnet.ru/tn_index_id_5374.htm

Monophosphothiamine is thiamine derivative used for the treatment of neuritis, polyneuritis, asthenic conditions (weakness), as an additional remedy for chronic blood circulation insufficiency, chronic gastritis accompanied by motor and secretory disorders functions of the stomach. Monophosphothiamine underwent metabolic phosphorylation to active metabolite thiamine pyrophosphate, that acts as a coenzyme in the different metabolic process.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Separation by ion exchange chromatography and spectrophotometric determination of cocarboxylase, monophosphothiamine and thiamine].	1971	5151224

Patents

Sample Use Guides

In Vivo Use Guide

0,01 - 0.03 g 3-4 times a day (after food) for 3-4 weeks.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:24:35 GMT 2023` Edited by `admin` on `Sat Dec 16 09:24:35 GMT 2023`
Record UNII	71F2V60NN0
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MONOPHOSPHOTHIAMINE INNER SALT

Common Name

English

THIAMINE ESTER PHOSPHATE

Common Name

English

THIAZOLIUM, 3-((4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL)-4-METHYL-5-(2-(PHOSPHONOOXY)ETHYL)-, INNER SALT

Systematic Name

English

THIAMINE PHOSPHORIC ACID ESTER

Common Name

English

THIAZOLIUM, 3-((4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL)-4-METHYL-5-(2-(PHOSPHONOOXY)ETHYL)-

Systematic Name

English

Code System Code Type Description

FDA UNII

71F2V60NN0