U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2017
422
Substance Class Protein
Created
by admin
on Fri Dec 15 16:50:58 UTC 2023
Edited
by admin
on Fri Dec 15 16:50:58 UTC 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
71492GE1FX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BENRALIZUMAB
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
Benralizumab [WHO-DD]
Common Name English
benralizumab [INN]
Common Name English
MEDI-563
Code English
BENRALIZUMAB [PURPLE BOOK CDER]
Common Name English
BENRALIZUMAB [MI]
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS IL5RA (INTERLEUKIN 5RECEPTOR SUBUNIT ALPHA, CD125)), HUMANIZED MONOCLONAL ANTIBODY
Common Name English
BENRALIZUMAB [JAN]
Common Name English
FASENRA
Brand Name English
BIW-8405
Code English
BENRALIZUMAB [USAN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 828221
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
NCI_THESAURUS C20401
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
FDA ORPHAN DRUG 660018
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
FDA ORPHAN DRUG 670018
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
FDA ORPHAN DRUG 670518
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
NDF-RT N0000193803
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
WHO-ATC R03DX10
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
FDA ORPHAN DRUG 838521
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
Code System Code Type Description
DRUG CENTRAL
5263
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
NCI_THESAURUS
C88594
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
DAILYMED
71492GE1FX
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
SMS_ID
100000167493
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
RXCUI
1989100
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
DRUG BANK
DB12023
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
MERCK INDEX
m12053
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
LACTMED
Benralizumab
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
USAN
XX-25
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
INN
9233
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
ChEMBL
CHEMBL1742991
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
CAS
1044511-01-4
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
WIKIPEDIA
BENRALIZUMAB
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
EVMPD
SUB181746
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
FDA UNII
71492GE1FX
Created by admin on Fri Dec 15 16:50:58 UTC 2023 , Edited by admin on Fri Dec 15 16:50:58 UTC 2023
PRIMARY
From To
1_22 1_96
1_148 1_204
1_224 3_214
1_230 2_230
1_233 2_233
1_265 1_325
1_371 1_429
2_22 2_96
2_148 2_204
2_224 4_214
2_265 2_325
2_371 2_429
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_301
N 2_301
Related Record Type Details
INTERLEUKIN-5 RECEPTOR SUBUNIT ALPHA
TARGET -> INHIBITOR
Binds to IL-5Rα and rapidly depletes levels of eosinophils and basophils through antibody-dependent cell-mediated cytotoxicity.
LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR III-A
TARGET->LIGAND
Related Record Type Details
BENRALIZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
Biological Half-life PHARMACOKINETIC
MOL_WEIGHT:APPROXIMATE CHEMICAL
NIH
NCATS
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