Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H26ClN3O |
| Molecular Weight | 335.872 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN(CCO)CCC[C@@H](C)NC1=CC=NC2=C1C=CC(Cl)=C2
InChI
InChIKey=XXSMGPRMXLTPCZ-CQSZACIVSA-N
InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/t14-/m1/s1
| Molecular Formula | C18H26ClN3O |
| Molecular Weight | 335.872 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Inhibition of HIV-1 replication by hydroxychloroquine: mechanism of action and comparison with zidovudine. | 1996 Nov-Dec |
|
| Private specificities can dominate the humoral response to self-antigens in patients with cryptogenic fibrosing alveolitis. | 2001 |
|
| Methotrexate-induced optic neuropathy. | 2002 Dec |
|
| Methimazole-induced lupus erythematosus: a case report. | 2003 Dec |
|
| Electrochemical study of hydroxychloroquine and its determination in plaquenil by differential pulse voltammetry. | 2003 Jun 1 |
|
| Frequency of adverse drug reactions in patients with systemic lupus erythematosus. | 2003 Mar |
|
| Assessing hydroxychloroquine toxicity by the multifocal ERG. | 2004 Jan |
|
| [Intolerance to hydroxychloroquine marketed in Spain (Dolquine) in patients with autoimmune conditions]. | 2004 Nov |
|
| Clinical outcome of patients with subcutaneous panniculitis-like T-cell lymphoma. | 2005 May |
|
| Shared decision-making based on different features of risk in the context of diabetes mellitus and rheumatoid arthritis. | 2007 Dec |
|
| Can HMG Co-A reductase inhibitors ("statins") slow the progression of age-related macular degeneration? The age-related maculopathy statin study (ARMSS). | 2008 |
|
| Retinal toxicity secondary to Plaquenil therapy. | 2008 Feb |
|
| [Chilblain lupus in an adolescent]. | 2008 Jul-Sep |
|
| Long-Term Alendronate Use Not without Consequences? | 2009 |
|
| [Combined basic therapy of rheumatoid arthritis with methotrexate and plaquenil]. | 2009 |
|
| Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseases. | 2009 |
|
| Autoimmune retinopathy in systemic lupus erythematosus: histopathologic features. | 2009 Apr 28 |
|
| Multiparameter phospho-flow analysis of lymphocytes in early rheumatoid arthritis: implications for diagnosis and monitoring drug therapy. | 2009 Aug 20 |
|
| Using multifocal ERG ring ratios to detect and follow Plaquenil retinal toxicity: a review : Review of mfERG ring ratios in Plaquenil toxicity. | 2009 Feb |
|
| [The ERG contribution in early diagnosis of chloroquine and hydroxychloroquine maculopathy]. | 2010 Apr |
|
| Vimentin compartmentalization in discoid lupus. | 2010 Feb |
|
| Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature. | 2010 Mar 23 |
|
| Ileocecal intussusception in the adult population: case series of two patients. | 2010 May |
|
| Spectral domain optical coherence tomography as an effective screening test for hydroxychloroquine retinopathy (the "flying saucer" sign). | 2010 Oct 21 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 06:43:28 GMT 2023
by
admin
on
Sat Dec 16 06:43:28 GMT 2023
|
| Record UNII |
70MN4ZH123
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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DTXSID70160180
Created by
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137433-23-9
Created by
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178395
Created by
admin on Sat Dec 16 06:43:28 GMT 2023 , Edited by admin on Sat Dec 16 06:43:28 GMT 2023
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70MN4ZH123
Created by
admin on Sat Dec 16 06:43:28 GMT 2023 , Edited by admin on Sat Dec 16 06:43:28 GMT 2023
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PRIMARY |