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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H26ClN3O
Molecular Weight 335.872
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDROXYCHLOROQUINE, (R)-

SMILES

CCN(CCO)CCC[C@@H](C)NC1=C2C=CC(Cl)=CC2=NC=C1

InChI

InChIKey=XXSMGPRMXLTPCZ-CQSZACIVSA-N
InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/t14-/m1/s1

HIDE SMILES / InChI

Molecular Formula C18H26ClN3O
Molecular Weight 335.872
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Spectral domain optical coherence tomography as an effective screening test for hydroxychloroquine retinopathy (the "flying saucer" sign).
2010-10-21
Ileocecal intussusception in the adult population: case series of two patients.
2010-05
[The ERG contribution in early diagnosis of chloroquine and hydroxychloroquine maculopathy].
2010-04
Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature.
2010-03-23
[Chilblain lupus in an adolescent].
2010-03-06
Vimentin compartmentalization in discoid lupus.
2010-02
Multiparameter phospho-flow analysis of lymphocytes in early rheumatoid arthritis: implications for diagnosis and monitoring drug therapy.
2009-08-20
Autoimmune retinopathy in systemic lupus erythematosus: histopathologic features.
2009-04-28
Using multifocal ERG ring ratios to detect and follow Plaquenil retinal toxicity: a review : Review of mfERG ring ratios in Plaquenil toxicity.
2009-02
Long-Term Alendronate Use Not without Consequences?
2009
[Combined basic therapy of rheumatoid arthritis with methotrexate and plaquenil].
2009
Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseases.
2009
Retinal toxicity secondary to Plaquenil therapy.
2008-02
Can HMG Co-A reductase inhibitors ("statins") slow the progression of age-related macular degeneration? The age-related maculopathy statin study (ARMSS).
2008
Shared decision-making based on different features of risk in the context of diabetes mellitus and rheumatoid arthritis.
2007-12
Clinical outcome of patients with subcutaneous panniculitis-like T-cell lymphoma.
2005-05
[Intolerance to hydroxychloroquine marketed in Spain (Dolquine) in patients with autoimmune conditions].
2004-11
Assessing hydroxychloroquine toxicity by the multifocal ERG.
2004-01
Methimazole-induced lupus erythematosus: a case report.
2003-12
Electrochemical study of hydroxychloroquine and its determination in plaquenil by differential pulse voltammetry.
2003-06-01
Frequency of adverse drug reactions in patients with systemic lupus erythematosus.
2003-03
Methotrexate-induced optic neuropathy.
2002-12
Private specificities can dominate the humoral response to self-antigens in patients with cryptogenic fibrosing alveolitis.
2001
Inhibition of HIV-1 replication by hydroxychloroquine: mechanism of action and comparison with zidovudine.
1996-11-01
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:37:43 GMT 2025
Edited
by admin
on Mon Mar 31 21:37:43 GMT 2025
Record UNII
70MN4ZH123
Record Status Validated (UNII)
Record Version
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Name Type Language
HYDROXYCHLOROQUINE, (R)-
Common Name English
(R)-(-)-HYDROXYCHLOROQUINE
Preferred Name English
ETHANOL, 2-(((4R)-4-((7-CHLORO-4-QUINOLINYL)AMINO)PENTYL)ETHYLAMINO)-
Systematic Name English
HYDROXYCHLOROQUINE, (-)-
Common Name English
ETHANOL, 2-((4-((7-CHLORO-4-QUINOLINYL)AMINO)PENTYL)ETHYLAMINO)-, (R)-
Common Name English
(R)-HYDROXYCHLOROQUINE
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID70160180
Created by admin on Mon Mar 31 21:37:43 GMT 2025 , Edited by admin on Mon Mar 31 21:37:43 GMT 2025
PRIMARY
CAS
137433-23-9
Created by admin on Mon Mar 31 21:37:43 GMT 2025 , Edited by admin on Mon Mar 31 21:37:43 GMT 2025
PRIMARY
PUBCHEM
178395
Created by admin on Mon Mar 31 21:37:43 GMT 2025 , Edited by admin on Mon Mar 31 21:37:43 GMT 2025
PRIMARY
FDA UNII
70MN4ZH123
Created by admin on Mon Mar 31 21:37:43 GMT 2025 , Edited by admin on Mon Mar 31 21:37:43 GMT 2025
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT