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Details

Stereochemistry ABSOLUTE
Molecular Formula C11H17NO3
Molecular Weight 211.2576
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ISOPROTERENOL, (+)-

SMILES

CC(C)NC[C@@H](O)C1=CC(O)=C(O)C=C1

InChI

InChIKey=JWZZKOKVBUJMES-LLVKDONJSA-N
InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3/t11-/m1/s1

HIDE SMILES / InChI

Molecular Formula C11H17NO3
Molecular Weight 211.2576
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Glucose uptake via SGLT-1 is stimulated by beta(2)-adrenoceptors in the ruminal epithelium of sheep.
2002-06
Vanillylamide-based propanolamine derivative displays alpha/beta-adrenoceptor blocking and vasodilating properties.
2002-06
Impaired intracellular signal transduction via cyclic AMP contributes to cerebral vasospasm in rats with subarachnoid hemorrhage.
2002-04
99mTc-glucarate for detection of isoproterenol-induced myocardial infarction in rats.
2002-02-21
Expression of human angiotensinogen-renin in rat: effects on transcription and heart function.
2002-02
The regulation of human vascular smooth muscle extracellular matrix protein production by alpha- and beta-adrenoceptor stimulation.
2002-02
Effect of an orally active Na+/H+ exchange inhibitor, SMP-300, on experimental angina and myocardial infarction models in rats.
2002-02
Bone marrow-derived regenerated cardiomyocytes (CMG Cells) express functional adrenergic and muscarinic receptors.
2002-01-22
Decreased SOD activity and increased nitrates level in rat heart with left ventricular hypertrophy induced by isoproterenol.
2002-01-19
Synergistic effect of nicorandil and amlodipine on mitochondrial function during isoproterenol-induced myocardial infarction in rats.
2002-01
Allosteric modulation of beta2-adrenergic receptor by Zn(2+).
2002-01
Effects of alpha- and beta-adrenergic stimulation on free magnesium concentrations in platelets from healthy and obese individuals.
2001-12
Differential effects of atropine and isoproterenol on inducibility of atrioventricular nodal reentrant tachycardia.
2001-12
Isoproterenol-induced cardiac hypertrophy: role of circulatory versus cardiac renin-angiotensin system.
2001-12
In vitro activity of polyhydroxycarboxylates against herpesviruses and HIV.
2001-11
Spironolactone and captopril attenuates isoproterenol-induced cardiac remodelling in rats.
2001-10
Activation of mitochondrial oxidative phosphorylation during (+/-)-isoproterenol-induced cell injury of myocardium.
2001-09-22
Calcineurin-GATA4 pathway is involved in beta-adrenergic agonist-responsive endothelin-1 transcription in cardiac myocytes.
2001-09-14
Report of a life-threatening arrhythmia after hospital discharge in a liver transplant recipient with previously unknown congenital long QT syndrome.
2001-09-01
A comparison of effects measured with isotonic and isometric recording: II. Concentration-effect curves for physiological antagonists.
2001-08
[Functional characterization of myocardial hypertrophy induced by isoproterenol and its regression].
2001-07
Different mechanisms of isoproterenol-induced and nitroglycerin-induced syncope during head-up tilt in patients with unexplained syncope: important role of epinephrine in nitroglycerin-induced syncope.
2001-07
A new aspect of view in synthesizing new type beta-adrenoceptor blockers with ancillary antioxidant activities.
2001-07
Catecholamines stimulate interleukin-6 synthesis in rat cardiac fibroblasts.
2001-07
Alterative and plastic insufficiency of cardiomyocytes: isoproterenol-induced damage to myocardium during anthracycline cardiomyopathy.
2001-06
beta-Adrenergic and endothelin receptor interaction in dilated human cardiomyopathic myocardium.
2001-06
Cardioprotective effects of Picrorrhiza kurroa against isoproterenol-induced myocardial stress in rats.
2001-05
PKC-beta is not necessary for cardiac hypertrophy.
2001-05
Evidence that ranolazine behaves as a weak beta1- and beta2-adrenoceptor antagonist in the rat [correction of cat] cardiovascular system.
2001-04
Elevated parasympathetic nerve tone in isoproterenol-induced neurally mediated syncope during head-up tilt testing.
2001-04
Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo.
2001-03-13
Neurohormonal regulation of secretion from isolated rat stomach ECL cells: a critical reappraisal.
2001-03-02
In vivo regulation of Na/Ca exchanger expression by adrenergic effectors.
2001-03
Interaction of calcitonin gene-related peptide (CGRP), substance P (SP) and conventional autonomic agonists in rat submandibular salivary peroxidase release in vitro.
2001-01-14
Paroxysmal tachycardia in children and teenagers with normal sinus rhythm and without heart disease.
2001-01
Lipopolysaccharide-induced tumor necrosis factor-alpha release is controlled by the central nervous system.
2001
Recurrent asystoles associated with vasovagal reaction during venipuncture.
2000-12
[Effects of isoprenaline on apoptosis related gene expression in rat myocardium cells].
2000-11
Pharmacological effects of an aldehyde type alpha/beta-adrenoceptor blocking agent with vasodilating properties.
2000-06
[Pharmacology of acebutolol in animals].
1975-12-31
Serum prolactin levels in rats following isoproterenol-induced myocardial infarction.
1975-12
[Prevention of isoproterenol-induced lesions in the rat myocardium by prenylamine].
1975-09-01
Effects of prindolol on isoproterenol-induced subendocardial ischaemia in dogs with multiple chronic coronary artery occlusion.
1975-07
Metabolic responses following isoproterenol-induced myocardial infarction in arteriosclerotic breeder vs. non-arteriosclerotic virgin and ovariectomized female rats.
1975-05-01
The use of practolol in supraventricular arrhythmias associated with acute illnesses.
1975-05
Metabolic response after isoproterenol-induced myocardial infarction in arteriosclerotic breeder vs nonarteriosclerotic virgin intact and gonadectomized male rats.
1975-04
Prolyl hydroxylase and collagen metabolism after experimental mycardial infarction.
1975-01
[Myocardial DNA and cell count following isoproterenol-induced myocardial necrosis in the rat].
1975
Method for the production of severe ventricular dysrhythmias in small laboratory animals.
1975
Membrane phospholipid metabolism in the isoproterenol-induced cardiomyopathy of the rat.
1975
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:41:00 GMT 2025
Edited
by admin
on Mon Mar 31 22:41:00 GMT 2025
Record UNII
70D2X5QMKK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
(+)-ISOPRENALINE
Preferred Name English
ISOPROTERENOL, (+)-
Common Name English
D-N-ISOPROPYLNOREPINEPHRINE
Common Name English
D-ISOPRENALINE
Common Name English
(S)-(+)-ISOPROTERENOL
Common Name English
ISOPRENALINE, (S)-
Common Name English
(S)-ISOPRENALINE
Common Name English
1,2-BENZENEDIOL, 4-((1S)-1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)-
Systematic Name English
D-ISOPROTERENOL
Common Name English
ISOPROTERENOL, D-
Common Name English
Code System Code Type Description
FDA UNII
70D2X5QMKK
Created by admin on Mon Mar 31 22:41:00 GMT 2025 , Edited by admin on Mon Mar 31 22:41:00 GMT 2025
PRIMARY
CAS
2964-04-7
Created by admin on Mon Mar 31 22:41:00 GMT 2025 , Edited by admin on Mon Mar 31 22:41:00 GMT 2025
PRIMARY
PUBCHEM
5808
Created by admin on Mon Mar 31 22:41:00 GMT 2025 , Edited by admin on Mon Mar 31 22:41:00 GMT 2025
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER