ALLYLTHIOUREA

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H8N2S
Molecular Weight	116.185
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=S)NCC=C

InChI

InChIKey=HTKFORQRBXIQHD-UHFFFAOYSA-N

InChI=1S/C4H8N2S/c1-2-3-6-4(5)7/h2H,1,3H2,(H3,5,6,7)

HIDE SMILES / InChI

Molecular Formula	C4H8N2S
Molecular Weight	116.185
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.abcam.com/allylthiourea-ab145720.html

Metabolic inhibitor. Selective inhibitor of ammonia oxidation. Probably acts through chelating the copper of the ammonia monooxygenase active site.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
copper of the ammonia monooxygenase active site 1 Target ID: copper of the ammonia monooxygenase active site Sources: http://www.abcam.com/allylthiourea-ab145720.html	Chelating Agent 142

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Reactions of allyl isothiocyanate with alanine, glycine, and several peptides in model systems.	2000 Aug	10956150
[Effect of acryl thiourea on liver pathologic changes in mice infected with Schistosoma japonicum].	2001	12572068
Evaluation of nitrification-inhibition measurements.	2001	11379092
Influence of sediment and pore-water composition on nitrite accumulation in a nitrate-perfused freshwater sediment.	2001 Aug	11471681
A proving of Thiosinamine.	2001 Jul	11479789
Respirometry techniques and activated sludge models.	2002	12360996
Dinitrogen oxide detection for process failure early warning systems.	2002	11936640
Provings and magic.	2002 Apr	12371456
Infrared spectra of new Re(III) complexes with thiourea derivatives.	2002 Dec	12511092
Effects of dental resin metabolites on estrogenic activity in vitro.	2003 Apr	15348454
A critical comparison of respirometric biodegradation tests based on OECD 301 and related test methods.	2003 Apr	12600385
Chemical and microbial hypotheses explaining the effect of wastewater treatment plant discharges on the nitrifying communities in freshwater sediment.	2003 Feb	12504130
Accelerated degradation of methyl iodide by agrochemicals.	2003 Jan 29	12537440
Schistosoma japonicum: establishment of a mouse model that demonstrates concomitant immunity.	2004 Jun	15198906
Construction of a reactive surface barrier to reduce fumigant 1,3-dichloropropene emissions.	2005 Aug	16152955
Changes in the biochemical oxygen demand procedure in the 21st edition of Standard Methods for the Examination of Water and Wastewater.	2005 Jul-Aug	16121508
Prediction of genotoxicity of chemical compounds by statistical learning methods.	2005 Jun	15962942
Chemical nitrite oxidation in acid solutions as a consequence of microbial ammonium oxidation.	2005 Jun 1	15984784
A rapid and simple respirometric biosensor with immobilized cells of Nitrosomonas europaea for detecting inhibitors of ammonia oxidation.	2005 Mar 15	15681195
Genotoxicity of dental resin polymerization initiators in vitro.	2006 Jan	16389469
Comparison Study of Different BOD Tests in the Determination of BOD(7) Evaluated in a Model Domestic Sewage.	2007	17671608
Impact of protozoan grazing on nitrification and the ammonia- and nitrite-oxidizing bacterial communities in activated sludge.	2007 May	17668014
Detection, isolation and characterization of a root-exuded compound, methyl 3-(4-hydroxyphenyl) propionate, responsible for biological nitrification inhibition by sorghum (Sorghum bicolor).	2008	18657214
Selectivity and recovery performance of phosphate-selective molecularly imprinted polymer.	2008 Jan 14	18082658
[Polyhydroxyalkanoate (PHA) synthesis by activated sludge microbes using acetic acid as carbon source].	2009 Aug 15	19799302
Use of allylthiourea to produce soluble methane monooxygenase in the presence of copper.	2009 Feb	19107472
Expression and characterization of two tyrosinases from the trematode Schistosoma japonicum.	2009 Feb	18972131
Processes impacting on benzene removal in vertical-flow constructed wetlands.	2009 Jan	18602259
Production of soluble methane monooxygenase during growth of Methylosinus trichosporium on methanol.	2009 Jan 1	18955091
p-Cresol biotransformation by a nitrifying consortium.	2009 Jun	19342073
Nitrous oxide emissions for early warning of biological nitrification failure in activated sludge.	2009 Mar	19167018
Biodegradation potential of wastewater micropollutants by ammonia-oxidizing bacteria.	2009 Nov	19772981
The characteristics of enriched nitrifier culture in the degradation of selected pharmaceutically active compounds.	2009 Nov 15	19615816
Nitrification inhibition activity, a novel trait in root exudates of rice.	2010	22476072
Kinetic parameters and inhibition response of ammonia- and nitrite-oxidizing bacteria in membrane bioreactors and conventional activated sludge processes.	2010 Dec 14	21275252
Biodegradation of oestrogens in nitrifying activated sludge.	2010 Oct	21046956

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:34:00 UTC 2023` Edited by `admin` on `Sat Dec 16 17:34:00 UTC 2023`
Record UNII	706IDJ14B7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALLYLTHIOUREA

Official Name

English

Allylthiourea [WHO-DD]

Common Name

English

THIOSINAMINUM

Common Name

English

THIOSINAMINE

Systematic Name

English

THIOSINAMINE [MI]

Common Name

English

allylthiourea [INN]

Common Name

English

THIOSINAMINUM [HPUS]

Common Name

English

NSC-1915

Code

English

1-ALLYL-2-THIOUREA

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C45175