MAGNESIUM ISOGLYCYRRHIZINATE

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Details

Stereochemistry	ABSOLUTE
Molecular Formula	C42H60O16.Mg
Molecular Weight	845.2212
Optical Activity	UNSPECIFIED
Defined Stereocenters	19 / 19
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MAGNESIUM ISOGLYCYRRHIZINATE

Structure Search

SMILES

[Mg++].C[C@]12CC[C@@](C)(C[C@@H]1C3=CC(=O)[C@@H]4[C@@]5(C)CC[C@H](O[C@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)C([O-])=O)C([O-])=O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)CC2)C(O)=O

InChI

InChIKey=OJIXTCWHYBRFHL-LEEOIRFPSA-L

InChI=1S/C42H62O16.Mg/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50;/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54);/q;+2/p-2/t19-,21+,22+,23+,24+,25+,26+,27-,28+,29+,30-,31-,34+,35+,38-,39+,40+,41-,42-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C42H60O16
Molecular Weight	820.9162
Charge	-2
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	19 / 19
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	Mg
Molecular Weight	24.305
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.cancer.gov/publications/dictionaries/cancer-drug/def/magnesium-isoglycyrrhizinate | https://www.ncbi.nlm.nih.gov/pubmed/30066834 | https://www.ncbi.nlm.nih.gov/pubmed/23681836

Magnesium isoglycyrrhizinate is a magnesium salt form of isoglycyrrhizinate, a derivative of glycyrrhizic acid extracted from the roots of the plant Glycyrrhiza glabra. Magnesium isoglycyrrhizinate has anti-inflammatory, antioxidant and hepatoprotective activities. The drug is believed to be a free radical scavenger and to modulate the activity of hepatic enzymes. Magnesium isoglycyrrhizinate was investigated in clinical trials to restore hepatic impairments caused by chemotherapy drugs and as a treatment of chronic liver diseases.

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:36:36 GMT 2025` Edited by `admin` on `Mon Mar 31 23:36:36 GMT 2025`
Record UNII	6ZH2XEE84P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

18.ALPHA.-GLYCYRRHIZIN MAGNESIUM

Preferred Name

English

MAGNESIUM ISOGLYCYRRHIZINATE

Common Name

English

MAGNESIUM GLYCYRRHIZINATE, 18.ALPHA.-

Common Name

English

Magnesium Isoglycyrrhizinate [WHO-DD]

Common Name

English

.ALPHA.-D-GLUCOPYRANOSIDURONIC ACID, (3.BETA.,18.ALPHA.,20.BETA.)-20-CARBOXY-11-OXO-30-NOROLEAN-12-EN-3-YL 2-O-.BETA.-D-GLUCOPYRANURONOSYL-, MAGNESIUM SALT (1:1)

Systematic Name

English

MAGNESIUM 18.ALPHA., 20.BETA.-HYDROXY-11-OXO-NOROLEAN-12-EN-3.BETA.-YL-2-O-.BETA.-D-GLUCOPYRANUROSYL-.ALPHA.-D-GLUCOPYRANOSIDURONATE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C275